Clinical trial · Interventional
Salicylic Acid Versus Cryotherapy for the Treatment of HPV1-induced Plantar Warts
Salicylic Acid Versus Cryotherapy for the Treatment of HPV1-induced Plantar Warts: a Randomized Controlled Trial
NCT05617950CI-TRIAL-00062198unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To evaluate whether salicylic acid was superior to cryotherapy for plantar warts
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Warts | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| cryotherapy | Other | — | UNRESOLVED |
| salicylic acid | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- salicylic acid
- description
- 30% salicylic acid
- interventionNames
- Other: salicylic acid
- type
- ACTIVE_COMPARATOR
- label
- cryotherapy
- description
- liquid nitrogen
- interventionNames
- Other: cryotherapy
Primary outcomes (1)
- measure
- cure rate at 12 weeks
- timeFrame
- 12 weeks since the initial treatment
- description
- A patient was considered to be cured if all warts were no longer visible and could not be palpated anymore.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 12 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with HPV1-induced plantar warts. * Total number of warts is ≤5. * Aged 12 years or older. Exclusion Criteria: * Patients are currently participating in another trial for the treatment of plantar warts. * Patients had received two or more consecutive sessions of cryotherapy, with an interval of no more than 4 weeks (The history of salicylic acid treatment was not considered as criteria for exclusion because high concentration salicylic acid is not commercially available in Chinese mainland). * Patients have taken immunosuppressant drugs (such as oral corticosteroids) during the past three months. * Patients have impaired healing eg due to diabetes, vitamin A deficiency, hyperthyroidism and hypothyroidism. * Patients have autoimmune diseases (such as systemic lupus erythematosus, dermatomyositis, scleroderma or other diseases). * Patients are pregnant or ready for pregnancies or breast-feeding. * Patients have cold intolerance (such as cold urticaria, cryoglobulinaemia, cold agglutinin syndrome or Raynaud's syndrome). * Patients have local pain intolerance. * Patients have local hypoesthesia. * Patients are unable to tolerate salicylic acid or cryotherapy.
References
Publications (0)
Data not yet available
No reference posted for this study.