Clinical trial · Observational
Molecular Characterization of Perivascular Epithelioid Cell Tumors
NCT05617105CI-TRIAL-00062190PEComesCellsunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Perivascular epithelioid cell tumors (PEComas) are rare and are characterized by the expression of myomelanocytic markers. They are a complex family that includes angiomyolipomas, lymphangioleiomyomatoses and other soft tissue and visceral tumors. Due to the low prevalence of these tumors, the natural history is unclear; furthermore, a molecular classification integrating clinical, pathological and molecular parameters has not been described to date.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Perivascular Epithelioid Cell Tumor, Malignant | Malignant PEComa | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- To retrospectively describe the percentage of tumors with FISH (Fluorescence In Situ Hybridization) identification of the TFE3 rearrangement out of 100 cases of PEComas diagnosed in France between 01 January 1990 and 15 September 2019
- timeFrame
- Files analysed retrospectively from January 01, 1990 to September 15, 2019 will be examined
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Year
Show eligibility criteria text
Inclusion criteria: * Major patient (≥18 years) * Minor patient (1 to 17 years old) * PEComas diagnosed in France between 01/01/1990 and 15/09/2019 and reviewed by a sarcoma referral pathologist Exclusion criteria : * Opposition of the patient (or the holders of parental authority) to participate in the study * Biological tissue from a patient who does not meet all the inclusion criteria * Classic triphasic angiomyolipoma or lymphangioleiomyomatosis * Inability to provide informed information to the subject * Patient under court protection * Patient under guardianship or curatorship
References
Publications (0)
Data not yet available
No reference posted for this study.