Clinical trial · Interventional
A Study of Tooth Erosion in People With Esophagogastric Cancer
Pilot Study of Dental Erosion as a Non-invasive Biomarker of Esophagogastric Cancer
NCT05612048CI-TRIAL-00106196active not recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The researchers are doing this study to find out more about what may lead to the loss of tooth enamel (the thin outer covering of the tooth) and how often it happens in people with esophagogastric cancer, colorectal cancer, pancreatic cancer, breast cancer, head and neck cancer, or non-small cell lung cancer, or a healthy volunteer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophagogastric Cancer | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intra-oral camera | Other | — | UNRESOLVED |
| Optional Salvia sample | Other | — | UNRESOLVED |
| Survey | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Patients diagnosed with esophagogastric cancer
- description
- Patients have completed the intervention once completing the survey, undergoing dental imaging and future patients will also provide an optional saliva sample.
- interventionNames
- Other: Survey
- Other: Intra-oral camera
- Other: Optional Salvia sample
- type
- EXPERIMENTAL
- label
- Patients diagnosed with colorectal, pancreatic, breast, head and neck, or non-small cell lung cancer
- description
- Patients undergo consenting and dental imaging during their routine visits at MSK.
- interventionNames
- Other: Survey
- Other: Intra-oral camera
- type
- EXPERIMENTAL
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Subject is willing and able to provide written informed consent. * Patients with a history of esophagogastric, HNSCC, PDAC, CRC, or NSCLC or healthy controls * Patients must be able to fully comprehend and complete the survey and be willing to have pictures taken of their teeth with a camera or intra-oral camera. * Patients must be able to understand English language or have access to adequate translation services. * Age ≥ 18 years old. Exclusion Criteria: * Subjects without evaluable molars or with significant molar dental work precluding dentists from assessing enamel status, Note: evaluable is defined as having bilateral assessable mandibular molars, or erosions present in the remaining assessable quadrants. * For healthy controls only, patients cannot have a non-skin cancer history nor presenting for a procedure evaluating reflux symptoms.
References
Publications (0)
Data not yet available
No reference posted for this study.