Clinical trial · Observational
Prospective Study of Sinonasal and Skull-base Tumours Management
Prospective Observational Study of Sinonasal and Skull-base Tumours Management in a Tertiary Referral Otorhinolaryngology Service
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This observational prospective clinical study aims to describe the epidemiology, management and outcome of patients with sinonasal and skull-base pathology (tumours and diseases with malignant clinical characteristics) in a tertiary otorhinolaryngology referral centre. The main questions it aims to answer are: * what is the caseload of patients with the included pathology in our centre * what are the results of management of these cases * what are the epidemiological characteristics of included patients * what is the quality of life of included patients.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Nasal Neoplasm | — | UNRESOLVED | — |
| Nasal Neoplasm Benign | — | UNRESOLVED | — |
| Sinonasal Disorder | — | UNRESOLVED | — |
| Sinus Disease | — | UNRESOLVED | — |
| Skull Base Neoplasms | Skull Base Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Skull Base Osteomyelitis | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Absence of the disease
- timeFrame
- twelve months after the treatment completion
- description
- Absence of the disease after the treatment has been completed
- measure
- Overall survival
- timeFrame
- twelve months after the treatment completion
- description
- Survival after the treatment has been completed
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * sinonasal and/or skull-base cancer * sinonasal disease expanding through the skull-base * the patient's written informed consent Exclusion Criteria: * lateral skull-base disease primarily originating in the temporal bone and without central skull-base involvement
References
Publications (1)
- DERIVEDVozel D, Urbancic J, Battelino S, Urbancic NB, Steiner N, Felbabic T, Bosnjak R. Quality of life in Slovenian patients with skull base tumours: cross-cultural adaptation and validation of a Slovenian skull base inventory. Radiol Oncol. 2026 Jan 21;60(1):106-113. doi: 10.2478/raon-2026-0007. eCollection 2026 Mar 1. PMID 41560283