Clinical trial · Interventional
Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will evaluate the impact of U=U messaging and counseling on gaps in the HIV care cascade for men, including testing uptake and ART initiation (Aim 1), achieving viral suppression and retention in care (Aim 2) in two provinces in South Africa. The U=U message communicates the compelling idea that PLHIV who take ART and have an undetectable viral load (\<200 copies/mL) cannot sexually transmit HIV. Additionally, the investigators will conduct a multi-method evaluation to inform future implementation of U=U messaging interventions (Aim 3).
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| HIV Infections | — | UNRESOLVED | — |
| Men | Multiple Endocrine Neoplasia | ALIAS | 0.90 |
| Treatment Adherence | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| U=U adherence messaging scripts | Behavioral | — | UNRESOLVED |
| U=U testing messaging scripts | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- U=U testing messaging scripts
- description
- Aim 1: Human-centred designed, behavioural nudge theory informed U=U messaging intervention to improve HIV testing uptake by men
- interventionNames
- Behavioral: U=U testing messaging scripts
- type
- EXPERIMENTAL
- label
- U=U adherence messaging scripts
- description
- Aim 2: Human-centred designed, behavioural nudge theory informed U=U messaging intervention to improve ART adherence, HIV viral suppression and retention in care
- interventionNames
- Behavioral: U=U adherence messaging scripts
- type
- NO_INTERVENTION
- label
- Standard of Care (SoC) messaging
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 15 Years
Show eligibility criteria text
Inclusion Criteria: AIM 1: 1. male 2. aged ≥15 years 3. present a study issued invitation card to site receptionist 4. ability to provide informed consent. AIM 2: 1. cis-gender men 2. aged ≥15 years 3. newly initiating ART (i.e., treatment naïve) or re-initiating ART after 6 months of being lost-to-care 4. live in Buffalo City or Cape Town Metro Health Districts 5. provide written informed consent
References
Publications (0)
Data not yet available