Clinical trial · Interventional
LymphoVenous Anastomosis to Prevent Breast Cancer Related Lymphedema
Lymfo-Veneuse Anastomosen Ter Preventie Van Lymphoedeem
NCT05601037CI-TRIAL-00082384LVARCTrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Lymphedema is defined as a chronic condition, caused by lymphostasis. A major part in the Western world consists of iatrogenic lymphedema caused by surgery to the lymph nodes of the axilla or groin. Prophylactic lymphovenous anastomosis (LVA) could be beneficial in the prevention of lymphedema of the extremities.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymphedema, Breast Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Axilla dissection + Lymphovenous anastomosis | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Axilla dissection + Lymphevenous Anastomosis
- description
- Surgical bypass between lymphatic vessel and vein
- interventionNames
- Procedure: Axilla dissection + Lymphovenous anastomosis
- type
- NO_INTERVENTION
- label
- Standard surgery
- description
- Standard surgery
Primary outcomes (1)
- measure
- The volume via circumferential measurements: swelling < 5%
- timeFrame
- 2 years
- description
- Comparing the volume of the arm at each study visit via circumferential measurements: swelling \< 5%
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * lymph node + breast cancer requiring dissection Exclusion Criteria: * previous lymphedema * BMI \>35
References
Publications (1)
- BACKGROUNDDepypere B, Vyncke T, Dhooghe N, Claes K, Blondeel P, Van Landuyt K. A Novel Technique for Preventive Lymphovenous Anastomosis: Anastomosing a Ligated Lymphatic Vessel. Plast Reconstr Surg Glob Open. 2021 Mar 22;9(3):e3509. doi: 10.1097/GOX.0000000000003509. eCollection 2021 Mar. PMID 33968557