Clinical trial · Interventional
Treatment of Epidermoid Cysts
A Prospective Clinical Trial Evaluating the Efficacy of 1.5% Sodium Tetradecyl Sulfate Foam Injection for the Treatment of Epidermoid Cysts
NCT05597995CI-TRIAL-00061783unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this study is to determine the efficacy, safety, tolerability, and patient satisfaction associated with the treatment of epidermoid cysts with injected 1.5% sodium tetradecyl sulfate (STS) foam.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Epidermoid Cyst | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Sodium Tetradecyl Sulfate | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Treatment with 1.5% sodium tetradecyl sulfate foam
- description
- each subject will have cyst contents aspirated through an 18g needle followed by an injection of 1.5% STS solution foamed 1:4 with air until foam is flowing out of the injection site.
- interventionNames
- Drug: Sodium Tetradecyl Sulfate
Primary outcomes (2)
- measure
- Investigator Assessment of EIC (Epidermal inclusion cysts) resolution
- timeFrame
- Day 60
- description
- Investigator Assessment of EIC (Epidermal inclusion cysts) resolution or recurrence Did the cyst resolve (involution or substantial decrease in size and clinical appearance)? (circle one) Resolved Did not resolve
- measure
- Cyst wall destruction on histologic examination as determined by a board-certified dermatopathologist
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adults in good general health based on the investigator's judgment and medical history aged 18-80 years old * Must be willing to sign a photography release and ICF. * Subject must be willing to undergo study procedures, including STS foam injection and excision with simple closure with an expected linear scar. * Epidermal inclusion cyst on the skin (not on mucosa or genitals) at least 4 mm in size * Negative urine pregnancy test at the time of study entry (if applicable) * Females will be either of non-childbearing potential defined as: 1. Having no uterus 2. No menses for at least 12 months. Or; Female subjects of childbearing potential must agree to use an effective method of birth control during the course of the study. All systemic birth control measures must be in consistent use for at least 30 days prior to study enrollment participation. Acceptable forms of birth control are below: <!-- --> 1. Oral contraceptive pill, injection, implant, patch, vaginal ring, intrauterine device 2. Intrauterine coil 3. Bilateral tubal ligation 4. Hysterectomy 5. Barrier method used with an additional form of contraception (e.g., sponge, spermicide, or condom) 6. Abstinence (If practicing abstinence, must agree to use a barrier method described above (4) If they become sexually active). 7. Vasectomized (must agree to use barrier method described above (4) if they become sexually active with an un-vasectomized partner). Exclusion Criteria: * Pregnancy or planned pregnancy during the study or currently breastfeeding. * Previously excised cysts or actively inflamed cysts will not be included in the study. * Presence of incompletely healed wound in the treatment area. * Any UNCONTROLLED systemic disease -a potential patient in whom therapy for a systemic disease is not yet stabilized will not be considered for entry into the study. * Significant history or current evidence of a medical, psychological, or other disorder that, in the investigator's opinion, would preclude enrollment into the study. * Allergy to STS. * Active dermatitis, active bacterial, neurologic, fungal, or viral infection in the proposed treatment area. * Inability to ambulate following the procedure. * Current participation or participation within 30 days prior to the start of this study in a drug or other investigational research study.
References
Publications (0)
Data not yet available
No reference posted for this study.