Clinical trial · Interventional
Mobile Intervention to Improve Adherence of Oral Anti-cancer Medications Among Acute Myeloid Leukemia Patients, the txt4AML Study
txt4AML: An Innovative Mobile Intervention to Improve Oral Anti-Cancer Medications Among Acute Myeloid Leukemia Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): staffing
Summary
Brief summary (as posted)
This clinical trial studies how well a mobile intervention consisting of a text messaging program and an electronic "smart" pill bottle with medication reminders works to improve adherence to oral anti-cancer medications among patients with acute myeloid leukemia (AML). Medication adherence is how well patients take medications as prescribed by their doctors, and good medical adherence is when patients take medications correctly. Poor medication adherence has been shown to be a barrier to effective treatment. Collecting feedback on patient experiences using the mobile intervention may help doctors design new methods and material for providing educational information to AML patients who are taking oral anti-cancer medications.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Myeloid Leukemia | Acute Myeloid Leukemia | CURATED_BROADER | 0.80 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Behavioral, Psychological or Informational Intervention | Other | — | UNRESOLVED |
| Quality-of-Life Assessment | Other | — | UNRESOLVED |
| Survey Administration | Other | — | UNRESOLVED |
| Text Message-Based Navigation Intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Health services research (text messages, smart pill bottle)
- description
- Patients receive interactive text messages to help with adherence to medications and a smart pill bottle with medication reminders on study.
- interventionNames
- Other: Text Message-Based Navigation Intervention
- Other: Behavioral, Psychological or Informational Intervention
- Other: Survey Administration
- Other: Quality-of-Life Assessment
Primary outcomes (6)
- measure
- Real-time oral anticancer medication (OAM) medication adherence
- timeFrame
- At baseline
- description
- Will be measured daily by AdhereTech wireless smart pill bottles, which are Health Insurance Portability and Accountability Act (HIPAA)-compliant Food and Drug Administration (FDA) Class I medical devices that monitor electronic tracking of bottle and percent of pills detected inside the bottle. Will be summarized using proportions and 95% Clopper-Pearson exact confidence intervals.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients diagnosed with acute myeloid leukemia (AML) * Patients will be or is taking venetoclax (or any other oral anticancer medication) as part of their first line therapy * Has a phone with text capabilities * Among patients aged 18 and older we will enroll participants regardless of race or ethnicity Exclusion Criteria: * Individuals who are terminally ill (defined as having less than 2 months to live) * Individuals for whom there is documentation of inability to provide consent in the medical record * Do not speak/read English * This study will exclude pediatric patients (defined as individuals under age 18 years)
References
Publications (0)
Data not yet available