Clinical trial · Observational
Comparison of HFNO and FMV on Desaturations During Panendoscopy Under General Anesthesia
Comparison of High-flow Nasal Oxygen Therapy and Face Mask Ventilation on Desaturations During Panendoscopy Under General Anesthesia
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Panendoscopy is a common procedure that requires deep and short anesthesia. The main challenge is the sharing of the airway between the anesthesia team and the surgical team. There are several methods to ensure oxygenation during this type of procedure: oro-tracheal intubation, jet ventilation, spontaneous ventilation anesthesia, apneic ventilation with intermittent face mask ventilation. There is no consensus regarding the best airway management technique for this procedure. Regardless of the method chosen to ensure oxygenation during this procedure, the risk of hypoxemia during desaturation episodes is significant. However, the use of HFNO seems to show a prolongation of apnea time without desaturations (\< 90% SpO2) and seems to allow the performance of panendocoscopies. In the Besançon University Hospital, since 2017, all panendoscopies are performed with HFNO. Before 2017, panendoscopies were performed under face mask ventilation. The main of the study hypothesis is that HFNO brought a gain in terms of safety, especially on the desaturation rate compared to face mask ventilation. The investigators will carry out a quasi-experimental study comparing two periods. The first period concerns the years 2015-2016. It aims to study patients who had panendoscopies performed under FMV. The second period covers the years 2018-2019. It aims to study patients who had panendoscopies performed under HFNO. The year 2017 is considered as the washout period necessary to avoid the learning effect of the HFNO introduced during that year.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| ENT Tumor | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- FaceMask Ventilation (FMV)
- description
- During the period from January 1, 2015, to December 31, 2016, all panendoscopies performed with FMV, whether urgent or scheduled and regardless of indication, were included. Panendoscopies performed with any other oxygenation method were excluded.
- label
- HFNO
- description
- During the period from January 1, 2018, to December 31, 2019, all panendoscopies performed with HFNO, urgent or scheduled and regardless of indication, were included. Panendoscopies performed with any other oxygenation method were excluded.
Primary outcomes (1)
- measure
- Proportion of patients with oxygen desaturation
- timeFrame
- more than 1 minute during the intervention
- description
- Proportion of patients with oxygen desaturation (SpO2 \< 90%) for more than 1 minute.
Secondary outcomes (5)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * major patients receiving panendoscopy * patients ventilated by face mask during the first period, * patients receiving oxygen by HFNO during the second period Exclusion Criteria: * Patients receiving ventilatory strategy other than those selected by time period. * Patients receiving panendoscopies performed with a method of oxygenation other than those defined in their period.
References
Publications (0)
Data not yet available