Clinical trial · Interventional
Same Day Discharge for Video-Assisted Thoracoscopic Surgery (VATS) Lung Surgery
Phase I Safety and Feasibility Pilot Study of Same-Day Discharge After Video-Assisted Thoracoscopic Surgery (VATS) Anatomical Lung or Wedge Resection (VALUE Trial)
NCT05583916CI-TRIAL-00061510VALUEunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Phase I to evaluate the safety and feasibility of same-day discharge in selected participants undergoing minimally-invasive lung surgery and who receive an enhanced recovery pathway.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Same Day Discharge - Video-Assisted Thoracoscopic Surgery (VATS) Lung | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Lung Cancer Patients
- description
- Patients with stage I or II primary lung cancer or pulmonary metastasis scheduled to undergo surgery.
- interventionNames
- Procedure: Same Day Discharge - Video-Assisted Thoracoscopic Surgery (VATS) Lung
Primary outcomes (4)
- measure
- Adverse Event Rate
- timeFrame
- 30 days post surgery
- measure
- Same Day Discharge Rate
- timeFrame
- Throughout the trial, from start until completion of surgery for all the patients, up to 12 months.
- measure
- Readmission Rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Signed or verbal informed consent by participant * Male and female adults, age 18 and above * Clinical stage I-II lung cancer (suspected, proven, unproven), or secondary pulmonary malignancy * BMI \< 35 * ECOG 0-1 * Eligible for surgery and lung cancer resection (FEV1 \> 60%, DLCO \> 60%) * Elective VATS anatomic resection (segmentectomy or lobectomy), or wedge resection * Capable caregiver for discharge home Exclusion Criteria: * Clinical stage III lung cancer * Surgery requiring pneumonectomy * Neoadjuvant therapy * Active pregnancy or breastfeeding * History of chronic pain syndromes * History of chronic opioid use * Concomitant major surgery indicated with current admission to hospital * Anticipated intraoperative complication including conversion to thoracotomy, major bleeding requiring blood transfusion, extensive adhesiolysis, injury to mediastinal structures, airway injury, nerve injury (phrenic, recurrent) * Need for epidural or patient-controlled intravenous analgesia * Need for urinary catheter
References
Publications (1)
- DERIVEDWalsh LC, Rokah M, Seitlinger J, Gallina FT, Huynh C, Gold MS, Sengupta A, Nicholls-Wallace T, Cronin E, Dehghani M, Rayes R, Mulder D, Sirois C, Rousseau M, Ferri L, Cools-Lartigue J, Costescu F, Najmeh S, Spicer JD. VALUE Trial: Phase 1 safety and feasibility study of same-day discharge after video-assisted thoracoscopic surgery lung resection. J Thorac Cardiovasc Surg. 2026 Jan;171(1):33-39. doi: 10.1016/j.jtcvs.2025.07.040. Epub 2025 Aug 6. PMID 40780316