Clinical trial · Observational
Feasibility of a Smart-Phone App for Patients With Advanced Renal Cell Carcinoma Undergoing Combination Immunotherapy
The Feasibility of an Educational and Monitoring Smart-Phone Application for Patients With Advanced Renal Cell Carcinoma Undergoing Combination Immunotherapy
NCT05579847CI-TRIAL-00098416completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to test and understand acceptability and preliminary effectiveness of a mobile educational app specifically customized to patients with advanced Renal Cell Carcinoma (RCC) receiving therapy with combination immunotherapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Renal Cell Carcinoma Stage IV | Renal Cell Carcinoma | CURATED_BROADER | 0.80 |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| eHEALS digital literacy test | Behavioral | — | UNRESOLVED |
| European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire | Behavioral | — | UNRESOLVED |
| mHealth Smart Phone Application | Other | — | UNRESOLVED |
| Patient Post Intervention Survey | Behavioral | — | UNRESOLVED |
| Weekly Quiz | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Study Participants
- description
- Participants with Stage IV Renal Cell Carcinoma will be recruited in the genitourinary medical oncology clinic at Moffitt Cancer Center. Upon consenting, participants will be provided with an mHealth interactive smart phone application.
- interventionNames
- Other: mHealth Smart Phone Application
- Behavioral: eHEALS digital literacy test
- Behavioral: Weekly Quiz
- Behavioral: European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire
- Behavioral: Patient Post Intervention Survey
Primary outcomes (1)
- measure
- Acceptability of Smart Phone Application
- timeFrame
- at 6 months
- description
- Patient's acceptability of the smart phone application for education will be captured in the patient post education survey.
Secondary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with Stage IV Renal Cell Carcinoma * Within 3 weeks from starting combination immune checkpoint blockade with tyrosine kinase inhibitor or multikinase inhibitor * Estimated survival of 6 months or more * Able to read and speak English Exclusion Criteria: * Unable to read or speak English * Enrolled in another clinical trial
References
Publications (1)
- DERIVEDRoman Souza G, Turner K, Gullapalli K, Paravathaneni M, Ionescu F, Semaan A, DeJesus AB, Trujillo G, Le C, Kim Y, Sun X, Raymond S, Schneider A, Manley B, Jain R, Gilbert S, Jim HSL, Spiess PE, Chahoud J. Feasibility of a Smartphone Application for Education and Symptom Management of Patients With Renal Cell Carcinoma on Combined Tyrosine Kinase and Immune Checkpoint Inhibitors. JCO Clin Cancer Inform. 2024 Jul;8:e2400044. doi: 10.1200/CCI.24.00044. PMID 39058967