Clinical trial · Interventional
Rectal Indomethacin to Prevent Acute Pancreatitis in EUS-FNA of Pancreatic Cysts
Randomized Trial of Rectal Indomethacin to Prevent Acute Pancreatitis in Patients Undergoing Endoscopic Ultrasound-guided Fine Needle Aspiration of Pancreatic Cysts
NCT05572788CI-TRIAL-00073435unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this randomized trial is to compare the rate of post-procedure pancreatitis in patients undergoing EUS-FNA of pancreatic cysts; patients will receive either a single dose of indomethacin or placebo administered rectally, during EUS-FNA.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cyst | — | UNRESOLVED | — |
| Pancreatitis, Acute | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EUS-guided fine needle aspiration of pancreatic cysts | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Rectal Indomethacin
- description
- Patients assigned to the Indomethacin group will receive100 mg of indomethacin administered per rectal route (two tablets of 50 mg indomethacin suppositories)
- interventionNames
- Procedure: EUS-guided fine needle aspiration of pancreatic cysts
- type
- PLACEBO_COMPARATOR
- label
- Placebo
- description
- Patients assigned to the Placebo group will receive two glycerin suppositories.
- interventionNames
- Procedure: EUS-guided fine needle aspiration of pancreatic cysts
Primary outcomes (1)
- measure
- Rate of post-procedure pancreatitis following EUS-guided fine needle aspiration of pancreatic cysts
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥ 18 years * Suspected or confirmed pancreatic cyst seen on imaging, requiring EUS-FNA Exclusion Criteria: * Unable to obtain consent from the participant or the participant's legally authorized representative (LAR) * Intrauterine pregnancy * Hypersensitivity reaction to Aspirin or NSAIDs * Patients with known history of chronic pancreatitis * Patients with known renal failure
References
Publications (0)
Data not yet available
No reference posted for this study.