Clinical trial · Observational
The Supraspinal Control of Lower Urinary Tract Function in Patients with Orthotopic Sigmoid Neobladder.
Neuroimaging Study of Supraspinal Control of Lower Urinary Tract Function in Patients with Orthotopic Sigmoid Neobladder.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Orthotopic sigmoid neobladder surgery is one of the ideal urinary diversion methods after radical cystectomy.In recent years, functional imaging studies have revealed brain regions related to urinary system function, but brain activity of lower urinary tract function in neobladder patients is still unclear.The aim of this study is to explore the brain activity of urination intention and self-controlled urination behavior in patients with orthotopic sigmoid neobladder by task-state functional magnetic resonance imaging (fMRI).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Orthotopic Neobladder | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Patients with orthotopic neobladder
- description
- Patients with orthotopic neobladder who met the inclusion criteria will be enrolled.Inclusion criteria :(1) being right-handed;(2) 3 months or more after operation;(3) No contraindications to fMIR examination;(4)Does not meet the relevant exclusion criteria.
Primary outcomes (2)
- measure
- The location of brain functional activation areas
- timeFrame
- 3 months
- description
- Areas of the brain where excitation or inhibition occurs in fMRI images
- measure
- The peak T-value size of the activation region
- timeFrame
- 3 months
- description
- Peak T values of activated or inhibited regions of the brain in fMRI images
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Being right-handed; 2. 3 months or more after operation; 3. No contraindications to fMIR examination; 4. Voluntarily sign informed consent. Exclusion Criteria: 1. History of bladder radiotherapy; 2. History of prostate cancer; 3. Suffering from diseases affecting abdominal pressure; 4. History of abnormal brain anatomy, craniocerebral surgery, craniocerebral tumor, and craniocerebral radiotherapy; 5. History of mental disorders, Parkinson's disease, Alzheimer's disease, epilepsy, cerebral infarction, cerebral hemorrhage; 6. Claustrophobia or carrying metal implants that are not suitable for fMRI examination; 7. Diseases affecting lower urinary tract function (such as spinal cord injury, diabetic peripheral neuropathy, etc.); 8. Urethral stricture; 9. Refusing to sign the informed consent form for clinical projects; 10. Other conditions that were not suitable for inclusion according to the investigator's judgment.
References
Publications (0)
Data not yet available