Clinical trial · Interventional
Effects of Different Doses of Vitamin D on Cancer-related Cognitive Impairment in Patients With Gastrointestinal Tumors
Effect of Different Doses of Vitamin D on Cancer-related Cognitive Impairment in Patients With Gastrointestinal Tumors: a Randomized Controlled Study
NCT05552729CI-TRIAL-00061004unknownPhase 1 / Phase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To explore the effect of different doses of vitamin D drugs on gastrointestinal cancer cancer-related cognitive impairment, so as to provide reference and basis for the clinical use of our cognitive function surgery nursing plan for patients with gastrointestinal cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cognitive Impairment | — | UNRESOLVED | — |
| Gastrointestinal Neoplasms | Digestive System Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Vitamin D | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- High dose group
- description
- A 2000IU vitamin D3 supplement was started the next day after surgery.
- interventionNames
- Drug: Vitamin D
- type
- ACTIVE_COMPARATOR
- label
- Low dose group
- description
- A 400IU vitamin D3 supplement was started the next day after surgery.
- interventionNames
- Drug: Vitamin D
- type
- NO_INTERVENTION
- label
- The control group.
- description
- No vitamin D3 supplement was started the next day after surgery.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with gastrointestinal tumors diagnosed by gastroscopy and histology and their family members * Elective surgery * Education level in primary school or above * Be able to fill in the questionnaire alone or under the guidance of the researcher * Informed consent and voluntary participation in this study Exclusion Criteria: * Patients with cognitive impairment (illiteracy less than 17 points, primary school less than 20 points, secondary school or above less than 24 points) or previous history of cognitive impairment, dementia and delirium confirmed by MMSE examination before surgery * Patients with life-threatening acute and chronic diseases * Patients with eye or ear diseases leading to rapid loss of hearing or vision without AIDS * Patients who have taken drugs related to improving cognitive function or drugs for psychiatric disorders * Patients who cannot take care of themselves or are physically disabled and unable to perform neurological function tests * Intraoperative hypoxemia (blood oxygen saturation \< 94％) more than 10 minutes * Patients who quit or died due to non-cooperation or emergency
References
Publications (0)
Data not yet available
No reference posted for this study.