Clinical trial · Interventional
A Clinical Study of Transaxillary Endoscopic and Open Thyroidectomy for PTC
A Multicenter, Randomized, Controlled Clinical Study on the Feasibility and Safety of Gasless Transaxillary Posterior Endoscopic and Open Thyroidectomy for Papillary Thyroid Cancer.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To evaluate the feasibility and safety of gasless transaxillary posterior endoscopic thyroidectomy (Resection of thyroid lobe and isthmus, lymph node dissection in the central area of the affected side) and open radical thyroidectomy (Resection of thyroid lobe and isthmus, lymph node dissection in the central area of the affected side) as the current standard surgical treatment mode in terms of feasibility and safety of radical thyroidectomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Papillary Thyroid Cancer | Thyroid Gland Papillary Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| COT(Conventional Open Thyroidectomy) | Procedure | — | UNRESOLVED |
| GTPET(Gasless Transaxillary Posterial Endoscopic Thyroidectomy) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Study Group
- description
- Gasless Transaxillary Posterial Endoscopic Thyroidectomy and Ipsilateral Central Lymph Node Dissection
- interventionNames
- Procedure: GTPET(Gasless Transaxillary Posterial Endoscopic Thyroidectomy)
- type
- ACTIVE_COMPARATOR
- label
- Control Group
- description
- Conventional Open Thyroidectomy and Ipsilateral Central Lymph Node Dissection
- interventionNames
- Procedure: COT(Conventional Open Thyroidectomy)
Primary outcomes (6)
- measure
- Early complication rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * The patient's informed consent; * 18 years old \< age \< 70 years old; * Papillary thyroid carcinoma (Bethesda grade V-VI) was pathologically diagnosed by fine needle aspiration biopsy of the primary thyroid tumor before surgery; * Color Doppler TI-RADS 4c-5 of primary thyroid tumor; * The preoperative clinical staging is T1, N0-1a, M0 (see diagnostic criteria for details; according to AJCC-8th TNM tumor staging); * It is expected that R0 surgical results can be obtained by performing single thyroid lobectomy and isthmus resection + ipsilateral central lymph node dissection; * Preoperative ASA score I-III. Exclusion Criteria: * Pregnant or lactating patients; * Suffering from serious mental illness; * Preoperative imaging examinations suggest that the tumor is located in the thyroid isthmus or involves bilateral lobes; * Preoperative imaging examinations suggest the possibility of cervical lateral lymph node or distant metastasis; * Hashimoto's thyroiditis combined with hyperthyroidism or abnormal thyroid function; * History of neck surgery; * History of thyroid surgery (including ablation therapy for thyroid nodules); * Family history of thyroid cancer; * History of childhood ionizing radiation exposure; * History of other malignant diseases within 5 years; * A history of unstable angina or myocardial infarction within 6 months; * History of cerebral infarction or cerebral hemorrhage within 6 months; * History of continuous systemic corticosteroid therapy within 1 month; * Concurrent surgical treatment of other diseases is required; * Patients who are judged by the investigator to be unsuitable to participate in this trial.
References
Publications (0)
Data not yet available