Clinical trial · Interventional
Propofol With Clonidine and Ketamine Throughout Colon Cancer Surgery
Consequences of Co-Administration of Propofol With Clonidine and Ketamine Throughout Colon Cancer Surgery
NCT05536362CI-TRIAL-00061710completedPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Study Showed that combining clonidine and ketamine together can increase the likelihood of achieving a sufficient level of anaesthesia while minimizing post-operative discomfort and inflammation.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Post Operative Pain | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| TCI Propofol Injection | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- TCI propofol mixed with clonidine and ketamine
- description
- Patient group,in which they got intravenous anaesthesia with TCI propofol mixed with clonidine and ketamine
- interventionNames
- Drug: TCI Propofol Injection
- type
- EXPERIMENTAL
- label
- TCI propofol mixed with a placebo
- description
- Control group,in which they received intravenous anaesthesia with TCI propofol mixed with a placebo (NaCl 0.9%)
- interventionNames
- Drug: TCI Propofol Injection
Primary outcomes (1)
- measure
- Measurement of Post-operative Pain
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 35 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: 1. ASA physical status I and II 2. Patients with cancer colon Exclusion Criteria: 1. participants with a history of heart, renal and liver cell failure. 2. allergic reaction to studied drugs, and history of epilepsy, 3. hydrodynamic instability, 4. chronic pain. 5. mental illness.
References
Publications (0)
Data not yet available
No reference posted for this study.