Clinical trial · Interventional
HFNO Reduces Hypoxia During Sedated Gastroscopy or Colonoscopy in High Risk Patients
High-flow Nasal Cannula Oxygenation Reduces the Incidence of Hypoxia During Gastroscopy or Colonoscopy Sedated With Propofol in High-risk Patients: a Multi Central Randomized Controlled Study
NCT05510388CI-TRIAL-00060463HRISKunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this study is to observe the preventive effects of high flow nasal oxygenation on the incidence of hypoxia during gastroscopy or colonoscopy sedated with propofol in high-risk patients.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Gastritis | — | UNRESOLVED | — |
| Intestinal Cancer | Malignant Intestinal Neoplasm | ALIAS | 0.90 |
| Intestine Adenoma | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| High-flow nasal cannula oxygenation | Device | — | UNRESOLVED |
| Regular nasal cannula oxygenation | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- High-flow nasal cannula oxygenation group
- interventionNames
- Device: High-flow nasal cannula oxygenation
- type
- ACTIVE_COMPARATOR
- label
- Regular nasal cannula oxygenation group
- interventionNames
- Device: Regular nasal cannula oxygenation
Primary outcomes (1)
- measure
- The incidence of hypoxia
- timeFrame
- Patients will be followed for the duration of hospital stay, an expected average of 2 hours
- description
- Hypoxia refers to 75%≤SpO2\<90%,\<60S
Secondary outcomes (4)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age ranging from 18 to 80, both sexes 2. Patients receiving selective gastroscopy or colonoscopy or gastroscopy and colonoscopy procedure 3. ASA Ⅲ\~Ⅳ 4. 18 kg/m2\<BMI\<28kg/m2 5. The anticipated operation time of the procedure shall be less than 30min. 6. Patients should clearly understand and voluntarily participate in the study, with signed informed consent. Exclusion Criteria: 1. Patients with nasal congestion, epistaxis, recent nasal trauma, recent nasal surgery, increased intracranial pressure and skull fracture, etc. who can not tolerate high-flow nasal cannula. 2. Patients diagnosed POCD 3. Patients clearly identified difficult airway 4. Patients with mechanical ventilation 5. Patients with acute respiratory infection and asthma 6. Patients with acute upper gastrointestinal hemorrhage accompanied by shock, severe anemia, gastrointestinal obstruction accompanied by retention of gastric contents 7. Patients with aortic stenosis and carotid stenosis 8. Patients allergic to sedatives such as propofol 9. Patients without civil capacity such as cognitive dysfunction
References
Publications (0)
Data not yet available
No reference posted for this study.