Clinical trial · Observational
Low Anterior Resection Syndrome After Rectum Resection for Rectal Carcinoma.
Erfassung Des Low Anterior Resection Syndroms Nach Rektumresektion Bei Patienten Mit Einem Rektumkarzinom - Eine österreichweite Multi-center Studie
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The ACO-ASSO (Austrian Society of Surgical Oncology) colorectal group and Austrian Working Group for Coloproctology present the LARS Austria study. It is a prospective, multicenter observational study. The primary objective of this study is to collect information about LARS (LARS score) and QoL (EORTC -CR29) in patients with non-metastatic rectal cancer who received therapy. As a secondary objective, the impact of radiotherapy on the occurrence of LARS will be investigated.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Incontinence | — | UNRESOLVED | — |
| Low Anterior Resection Syndrome | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Detection of Low Anterior Resection Syndrome (LARS) after anterior rectal resection.
- timeFrame
- 3 months after the rectum resection or after the closure of a protective ileostomy or after an Chemoradiation in case of watch and wait
- description
- Occurrence of Low Anterior Resection Syndrome (LARS) will be measured with an LARS Score. The score ranges from 0 to 42 is divides into no LARS (0 to 20 points), minor LARS (21 to 29 points), and major LARS (30 to 42 points)
- measure
- Detection of Low Anterior Resection Syndrome (LARS) after anterior rectal resection.
- timeFrame
- 6 months after the rectum resection or after the closure of a protective ileostomy or after an Chemoradiation in case of watch and wait
- description
- Occurrence of Low Anterior Resection Syndrome (LARS) will be measured with an LARS Score. The score ranges from 0 to 42 is divides into no LARS (0 to 20 points), minor LARS (21 to 29 points), and major LARS (30 to 42 points)
- measure
- Detection of Low Anterior Resection Syndrome (LARS) after anterior rectal resection.
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age: 18 to 99 years * Patients with biopsy-verified rectal cancer. * Patients scheduled for elective sphincter-preserving rectal surgery * Patients scheduled for neoadjuvant RCTx (Chemo-radiation) (concept: short course radiation, conv. fractionated RCTx, total neoadjuvant therapy(TNT)) * Signed consent (ICF) Exclusion Criteria: * Patients younger than 18 years * Patients without signed informed consent * Metastatic carcinoma * terminal colostomy ( APR (abdominoperineal resection),...)
References
Publications (0)
Data not yet available