Clinical trial · Observational
Meaning-Centered Psychotherapy at Home
A Pragmatic Randomized Control Trial of Nurse-Delivered Brief Meaning Centered Psychotherapy for Homebound Palliative Care Patients
NCT05495737CI-TRIAL-00094891active not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 16, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260916-000001
Summary
Brief summary (as posted)
The purpose of this study is to train nurses from the VNS Health Visiting Nurse Service to deliver Meaning-Centered Psychotherapy for Palliative Care Patients (MCP-PC) to homebound people, and to evaluate how effective MCP-PC is for people with cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Nurse-Patient Relations | — | UNRESOLVED | — |
| Psychology, Social | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Meaning-Centered Psychotherapy/MCP-PC | Behavioral | — | UNRESOLVED |
| Meaning-Centered Psychotherapy/MCP-PC Training | Behavioral | — | UNRESOLVED |
| Treatment As Usual/TAU | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (5)
- label
- Phase 1: Nurse Participants
- description
- n=8-10 nurses
- interventionNames
- Behavioral: Meaning-Centered Psychotherapy/MCP-PC Training
- label
- Phase 1: Patient Participants
- description
- n=8-10 patients
- interventionNames
- Behavioral: Meaning-Centered Psychotherapy/MCP-PC
- label
- Phase 2: Nurse Participants
- description
- n=8-10 nurses
- interventionNames
- Behavioral: Meaning-Centered Psychotherapy/MCP-PC Training
- label
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Participant Inclusion Criteria: Nurses (all phases): * Per self-report, providing direct care services at VNS Health * Per self-report, fluent in English\*\* * Per self-report, is age 18 or older Patients (all phases): * Per health record and/or self-report, is a patient in the VNS Health home health agency division (post-acute care) * Per health record and/or self-report, is age 18 or older * Per health record, has a cancer diagnosis and a rating of ≥ 2 on Symptom Control Scale * Per health record and/or self-report, fluent in English\*\* * Has a score of ≥ 4 on Callahan cognitive screener * Has a score of ≥ 4 on Distress Thermometer (N/A for Training Case Participants) * Language verification: For both nurses and patients, prior to enrollment, all will be asked the following two questions by a Clinical Research Coordinator (CRC) to verify English fluency necessary for participation in the study: 1. How well do you speak English? (must respond "very well" or "well" when given the choices of Very well, Well, Not well, Not at all, Don't know, or Refused) 2. What is your preferred language for healthcare? (must respond English) Participant Exclusion Criteria: Nurses (all phases): * Per self-report, planning to leave position at VNS Health in the next 6 months Patients (all phases): * Per health record and/or self-report, has a diagnosis of Alzheimer's, dementia, or other organic brain disorder and in the judgment of the PIs is unable to meaningfully participate. * Per health record, has impaired decision-making capacity * Per health record and/or self-report, is permanently placed in a nursing home * Per health record and/or self-report, is currently receiving Hospice care
References
Publications (1)
- DERIVEDSaracino RM, Park EY, Onorato N, Pessin H, McDonald M, Demirjian C, Schofield E, Rosenfeld B, Breitbart W, Applebaum AJ. A pragmatic randomized controlled trial of nurse-delivered brief Meaning Centered Psychotherapy at Home (MCP-H) for individuals with advanced cancer: Study protocol. J Geriatr Oncol. 2025 Nov;16(8):102736. doi: 10.1016/j.jgo.2025.102736. Epub 2025 Oct 3. PMID 41045824