Clinical trial · Interventional
Serratus Anterior Plane Block to Prevent Chronic Postoperative Pain in Breast Cancer
Serratus Anterior Plane Block to Prevent Chronic Pain in Breast Cancer Surgery: A Randomized Controlled Trial
NCT05494281CI-TRIAL-00060987USB22unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Chronic postoperative pain (CPP) remains a disturbing and obscure clinical problem. The hypothesis of this trial is that a peripheral block of the serratus anterior plane block type preoperatively after a modified radical mastectomy makes it possible to reduce the intensity and incidence of chronic post-surgical pain in breast cancer.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Neoplasms | Breast Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Pain, Chronic | — | UNRESOLVED | — |
| Pain, Postoperative | — | UNRESOLVED | — |
| Post-Mastectomy Chronic Pain Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Serratus Anterior Plane Block with local anesthetic | Procedure | — | UNRESOLVED |
| Serratus Anterior Plane Block with saline solution | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Placebo
- interventionNames
- Procedure: Serratus Anterior Plane Block with saline solution
- type
- EXPERIMENTAL
- label
- Serratus anterior plane block
- interventionNames
- Procedure: Serratus Anterior Plane Block with local anesthetic
Primary outcomes (2)
- measure
- Chronic postoperative pain at 3 months
- timeFrame
- 3 months after surgery
- description
- A question will be asked to patients : "Throughout our lives, most have had pain (like headaches, sprains and toothaches). Have you had pain other than these types of pain on a daily basis since your surgery? " The answer "yes" or "no" will determine the outcome
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Having an age greater than or equal to 18 years and less than 70 years * Having given written consent for participation in the study and the use of personal and medical data * Having a physical status of class I, II or III of the American Society of Anesthesiologists Exclusion Criteria: * Patients who expressed their refusal to participate in the study * Patients unable to express their non-objection to participation in the study * American Society of Anesthesiologists class \> III patients * Known allergy to local anesthetics * A contraindication to performing a peripheral nerve block (such as an acquired, constitutional or drug clotting disorder or infection at the nerve block injection site) * Morbid obesity (body mass index greater than 40 kg/m²) * Chronic use of opioids * Inability to use the patient controlled analgesia device * The existence of preoperative pain * History of neuropathy or neurological pathology * The existence of catastrophism or anxiety diagnosed preoperatively
References
Publications (0)
Data not yet available
No reference posted for this study.