Clinical trial · Interventional
Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases
Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases: A Pilot Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Piezoelectric drived microneedling treats refractory skin disorders using hollow microneedles assisted by ultrasound. Mechanically, the injection of medicine by hollow microneedling could makes the distribution of medicine more evenly. And the addition of ultrasound technique improves the effectiveness of microneedling. Investigators plan to conduct a pilot study to investigate the efficacy of using piezoelectric drived microneedles in treating refractory skin diseases.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hypertrophic Scar | — | UNRESOLVED | — |
| Keloid | — | UNRESOLVED | — |
| Plantar Wart | Verruca Plantaris | ALIAS | 0.90 |
| Skin Diseases | — | UNRESOLVED | — |
| Skin Tumor | Skin Neoplasm | ALIAS | 0.90 |
| Warts | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 5-ALA (a photosensitizer for photodynamic therapy). | Drug | — | UNRESOLVED |
| Piezoelectric drived microneedling | Procedure | — | UNRESOLVED |
| Triamcinolone acetonide(scar)/5-ALA(others) | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Traditional injection
- description
- Intralesional injection of drug by traditional injection needle. This is the traditional approach for drug delivery recommended by international guidelines for each skin diseases.
- interventionNames
- Drug: Triamcinolone acetonide(scar)/5-ALA(others)
- type
- EXPERIMENTAL
- label
- Piezoelectric drived microneedling
- description
- Intralesional injection of drug by piezoelectric drived microneedles.
- interventionNames
- Procedure: Piezoelectric drived microneedling
- Drug: 5-ALA (a photosensitizer for photodynamic therapy).
Primary outcomes (2)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 16 Years
Show eligibility criteria text
Inclusion Criteria: * Age over 16 years * Diagnosed by 2 or more professional dermatologists * Willing to underwent a new treatment modality * Follow up is easy to conduct Exclusion Criteria: * Poor general condition * Bleeding tendency * Allergy to drug
References
Publications (0)
Data not yet available