Clinical trial · Observational
Characterizing Sleep Among Long-term Survivors of Childhood Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The patients are being asked to take part in this clinical trial because they received cancer treatment as a child at St. Jude. The study comprehensively examines sleep among three distinct diagnostic groups of survivors in the SJLIFE cohort: ALL, CNS tumors, and non-CNS solid tumors. Primary Objective The primary aim of this protocol is to estimate the prevalence of various sleep disorders among long-term survivors of childhood ALL, CNS tumors, and non- CNS solid tumors. Exploratory Objective The exploratory objective of the study is to explore associations between the prevalence of sleep disorders and clinical outcomes collected in SJLIFE.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| ALL, Adult | Adult Acute Lymphoblastic Leukemia | ALIAS | 0.90 |
| CNS Tumor | Central Nervous System Neoplasm | ALIAS | 0.90 |
| Solid Tumor | Solid Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (7)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CNS Vital Signs (Thinking) Testing | Diagnostic Test | — | UNRESOLVED |
| Echocardiography/EKG | Diagnostic Test | — | UNRESOLVED |
| Health Questionnaires, Sleep Surveys & Sleep Diary | Other | — | UNRESOLVED |
| Neurocognitive (Thinking) Testing | Other | — | UNRESOLVED |
| Physical Function | Diagnostic Test | — | UNRESOLVED |
| Pulmonary Function | Diagnostic Test | — | UNRESOLVED |
| Remote Polysomnography | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- On campus
- description
- SJLIFE Study Campus Visit
- interventionNames
- Other: Neurocognitive (Thinking) Testing
- Other: Health Questionnaires, Sleep Surveys & Sleep Diary
- Diagnostic Test: Echocardiography/EKG
- Diagnostic Test: Pulmonary Function
- Device: Remote Polysomnography
- Diagnostic Test: Physical Function
- label
- Remote
- description
- SJLIFE cohort: ALL, CNS tumors, and non-CNS solid tumors
- interventionNames
- Diagnostic Test: CNS Vital Signs (Thinking) Testing
- Other: Health Questionnaires, Sleep Surveys & Sleep Diary
- Device: Remote Polysomnography
Primary outcomes (7)
- measure
- Insomnia Severity Index (ISI)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Participant in SJLIFE and \> 5 years from diagnosis. * \>18 years of age at time of enrollment. * Diagnosed with ALL (treated with CRT or chemotherapy only) or CNS tumors (posterior fossa tumors or supratentorial tumors) or non-CNS solid tumors (with abdominal or chest radiation or bilateral retinoblastoma survivors). * Participant was less than 21 years of age at time of diagnosis. * Speaks and understands English (polysomnography device speaks to patients only in English). * Remote participant must have Wi-Fi access Exclusion Criteria: * Estimated intelligence score \<80. * Currently prescribed an intervention for a sleep disorder. * Survivor of craniopharyngioma. * Survivor of Hodgkin Lymphoma. * Relapsed or treated with hematopoietic stem cell therapy. * Brain injury unrelated to cancer diagnosis or therapy. * Pulmonary injury unrelated to cancer diagnosis or therapy.
References
Publications (0)
Data not yet available