Clinical trial · Interventional
Exercise Program for Colorectal Older Patients
Effect of a Personalized Physical Exercise Program on Functional Capacity and Quality of Life in Older Colorectal Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Exercise for COlorectal OLder patients (ECOOL program) is randomized controlled trial to assess the effects of an exercise program on physical function and health-related quality of life of patients 75 years and older with colorectal cancer undergoing surgery. ECOOL is a multicomponent home-based exercise intervention focused on the development of strength, balance, gait ability and inspiratory muscle function of older patients who receive weekly telephone follow-up from cancer diagnosis to 3 months after surgery. The investigators expect that ECOOL program will improve physical function and health-related quality of life of older patients 3 months after surgery and to maintain these benefits up to 6 months after surgery compared with the control group receiving usual care.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aged | — | UNRESOLVED | — |
| Colorectal Neoplasms | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Enhanced Recovery After Surgery | Procedure | — | UNRESOLVED |
| Home-based multicomponent exercise program (EXE) | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Control
- description
- Usual care (i.e., 'Enhanced Recovery After Surgery' (ERAS) protocol)
- interventionNames
- Procedure: Enhanced Recovery After Surgery
- type
- EXPERIMENTAL
- label
- Home-based multicomponent exercise program
- description
- Complete a home-based multicomponent exercise program from diagnosis to 3 months after surgery in addition to ERAS protocol.
- interventionNames
- Procedure: Enhanced Recovery After Surgery
- Behavioral: Home-based multicomponent exercise program (EXE)
Primary outcomes (4)
- measure
- Change in Health-related Quality of Life (HRQoL) of cancer patients
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged 75 years or older diagnosed with colorectal cancer. * Patients included in colorectal surgery waiting list of the Hospital General Universitario Gregorio Marañon (Madrid, Spain) * Patients able to communicate, understand and sign the informed consent. Exclusion Criteria: * Patients finally excluded for colorectal surgery. * Patients with absolute contraindications to exercise * Walk disability (FAC \<2) * Severe cognitive impairment (MMSE \<18) * Terminal illness
References
Publications (1)
- DERIVEDMacias-Valle A, Rodriguez-Lopez C, Gonzalez-Senac NM, Mayordomo-Cava J, Vidan MT, Cruz-Arnes ML, Jimenez-Gomez LM, Dujovne-Lindenbaum P, Perez-Menendez ME, Ortiz-Alonso J, Valenzuela PL, Rodriguez-Romo G, Serra-Rexach JA. Exercise effects on functional capacity and quality of life in older patients with colorectal cancer: study protocol for the ECOOL randomized controlled trial. BMC Geriatr. 2023 May 22;23(1):314. doi: 10.1186/s12877-023-04026-6. PMID 37211611