Clinical trial · Interventional
Pre-therapeutic Analysis of the Individual Radiosensitivity of Cancer Patients in Luxembourg (APRI-Lux): Prospective National Interventional Study With Minimal Risk
NCT05433974CI-TRIAL-00059317unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Pre-therapeutic analysis of the individual radiosensitivity of cancer patients in Luxembourg
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Radiation Toxicity | — | UNRESOLVED | — |
| Radiosensitivity | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood sample collection | Biological | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Radiosensitivity
- description
- Patient who agree to participate in this research study will have blood sample collected in order to perform the RadioDtect test.
- interventionNames
- Biological: Blood sample collection
Primary outcomes (1)
- measure
- Validation of RadioDtect test on early radiation-induced toxicity
- timeFrame
- 3 months
- description
- prospectively validate the predictive capacities of the RadioDtect individual radiosensitivity blood test on early radiation-induced toxicity. The validation will be based on ATM protein assay and rate of acute toxicities of grade ≥ 2 to 3 months according to NCI-CTCAE v4.03 criteria
Secondary outcomes (1)
- measure
- Validation of RadioDtect test on delayed radiation-induced toxicity
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient over 18 years old * Patient with an indication for curative radiotherapy * Patient having given his signed written informed consent before any specific procedure of the protocol. Exclusion Criteria: * Patient with a contraindication to radiotherapy * Patient with an indication for palliative radiotherapy * Patient with a history of radiotherapy in the area where the cancer is located * Patient unable to submit to the medical follow-up of the trial for geographical, social or psychological reasons.
References
Publications (0)
Data not yet available
No reference posted for this study.