Clinical trial · Interventional
Prevention of Functional and Cognitive Impairment in Hospitalized Oncogeriatric Patients
Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program in Hospitalized Oncogeriatric Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Hospitalized older patients usually remain bedridden for many hours and this may lead to the appearance of unwanted negative consequences, such as cognitive or physical decline upon discharge. Our study will analyze whether an intervention consisting of a multicomponent training programme applied to patients over the age of 60 who are hospitalized for acute medical conditions in an Oncology Department of a tertiary hospital improves functional capacity and cognitive function. A total of 50 hospitalized older adult patients will be recruited in the Hospital Universitario de Navarra, Pamplona, Spain. The participants will be randomized and included in an exercise intervention (n = 25) or a control (n = 25) group (hospital usual-care). The intervention consists of a multicomponent exercise training programme that will take place for 3 consecutive days (2 sessions/day). The control group will receive usual hospital care, which will include physical rehabilitation when needed. Functional and cognitive impairment after and during acute hospitalization in older adults are major determinants of the later need for health resources. If our hypothesis is correct and shows that a multicomponent, individualized and progressive exercise programme is an effective therapy for improving the functional capacity of acutely hospitalized older patients compared to usual care, a change in the current system of hospitalization may be justified in oncogeriatric patients with medical conditions
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aging | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Debility | — | UNRESOLVED | — |
| Hospital Acquired Condition | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Multicomponent exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Multicomponent Exercise
- description
- The intervention will consist of a multicomponent exercise training programme, which will include supervised progressive resistance exercise training, balance training, and walking for 3 consecutive days. During the training period, patients will be trained in 20-minute sessions twice a day (morning and evening).
- interventionNames
- Behavioral: Multicomponent exercise
- type
- NO_INTERVENTION
- label
- Usual care
- description
- Participants randomly assigned to the usual care group will receive normal hospital care, including physical rehabilitation when needed
Primary outcomes (2)
- measure
- Change in functional capacity: Short Physical Performance Battery test (SPPB; Spanish versión)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Age \> 65 years * Barthel Index ≥60 points * Able to ambulate (with/without assistance) * Sign the informed consent * Able to communicate Exclusion Criteria: * Expected length of stay \< 6 days * Terminal illness * Very severe cognitive decline (i.e., GDS 7) * Uncontrolled arrhythmias, acute pulmonary embolism, acute myocardial infarction or limb bone fracture in the past 3 months.
References
Publications (1)
- DERIVEDFerrara MC, Zambom-Ferraresi F, Castillo A, Delgado M, Galbete A, Arrazubi V, Morilla I, Zambom-Ferraresi F, Fernandez Gonzalez de la Riva ML, Vera Garcia R, Martinez-Velilla N. Effects of an individualised exercise program in hospitalised older adults with cancer: A randomised clinical trial. J Nutr Health Aging. 2025 Jan;29(1):100424. doi: 10.1016/j.jnha.2024.100424. Epub 2024 Nov 29. PMID 39615400