Clinical trial · Interventional
A Multifaceted Telemedicine-Based Intervention to Improve Outcomes of Cancer Patients Admitted to the ICU
A Multifaceted Telemedicine-Based Intervention to Improve Outcomes of Cancer Patients Admitted to the ICU : A Stepped Wedge Cluster-randomised Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Admission to the intensive care unit (ICU) is a common event in patients treated for solid tumors or hematologic malignancies. A volume-outcome relationship has been shown in these patients, with a mortality rate decreasing from 70% in low-volume centres to 30-40% in high-volume centres. We hypothesize that providing the low-volume centres with assistance from experts working in high-volume centres for the management of critically-ill cancer patients can bring down mortality to the values seen in high-volume centres. The main objective of this study is to evaluate whether combining three knowledge-transfer methods (videoconference-based forum, educational sessions, and dissemination of published work) increases the survival of cancer patients managed in low-volume centres to the values seen in high-volume centres. The main endpoint is all-cause mortality at hospital discharge.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Active Malignancies | — | UNRESOLVED | — |
| Life Threatening Complication of the Malignancy or Its Treatments | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Standard of care arm | Other | — | UNRESOLVED |
| Telemedicine-based intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Comparator Arm
- description
- Classic expertise (as routinely performed in the participating ICU)
- interventionNames
- Other: Standard of care arm
- type
- EXPERIMENTAL
- label
- Telemedicine-based intervention
- description
- Telemedicine-based expert advice.
- interventionNames
- Other: Telemedicine-based intervention
Primary outcomes (1)
- measure
- All-cause mortality
- timeFrame
- at hospital discharge (up to 28 days)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
Show eligibility criteria text
Inclusion Criteria: 1. Adult patients (\> 18 years old) 2. Active malignancy; 3. ICUs seeking for an advice must admit fewer than 30 patients with active cancer per year; 4. Patients has been urgently admitted in the ICU for a life threatening complication of the malignancy or its treatments. Exclusion Criteria: 1. Isolated HIV infection or AIDS; 2. ICU admission complicating scheduled surgery, 3. Treatment-limitation decisions at admission; 4. No coverage by the French statutory health insurance system, 5. Pregnant or breastfeeding
References
Publications (0)
Data not yet available