Clinical trial · Observational
Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy
NCT05417672CI-TRIAL-00059059unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Malnutrition is common in patients with lung cancer. In patients with malnutrition risk, the risk of complications is high both in the perioperative, early and late postoperative periods. Malnutrition is an independent risk factor for length of hospital stay and cost in these patients. Patients with lung cancer may have many morbidities in postoperative period, especially problems with wound healing. Therefore, assessment of the nutritional status of patients with lung cancer should begin at the diagnosis stage.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Malnutrition | — | UNRESOLVED | — |
| Nutritional Deficiency | — | UNRESOLVED | — |
Interventions
Interventions (7)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Anthropometric measurements | Diagnostic Test | — | UNRESOLVED |
| Glasgow Prognostic Score | Diagnostic Test | — | UNRESOLVED |
| Handgrip strength test | Device | — | UNRESOLVED |
| Mini Nutritional Assessment | Diagnostic Test | — | UNRESOLVED |
| Nutritional Risk Index | Diagnostic Test | — | UNRESOLVED |
| Nutritional Risk Screening-2002 | Diagnostic Test | — | UNRESOLVED |
| Prognostic Nutritional Index | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Lung cancer scheduled lobectomy
- interventionNames
- Diagnostic Test: Nutritional Risk Screening-2002
- Diagnostic Test: Nutritional Risk Index
- Diagnostic Test: Mini Nutritional Assessment
- Diagnostic Test: Glasgow Prognostic Score
- Diagnostic Test: Prognostic Nutritional Index
- Diagnostic Test: Anthropometric measurements
- Device: Handgrip strength test
Primary outcomes (4)
- measure
- Postoperative complications
- timeFrame
- a month after the surgery
- description
- dysrhythmia, acute coronary syndrome, sepsis, mediastinitis, pneumonia, surgical site infection, prolonged air leak
- measure
- Length of stay in the intensive care unit
- timeFrame
- up to 30 days
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Having a diagnosis of lung cancer * Lung lobectomy operation will be performed * 18 years and older patients * Having an American Society of Anesthesiologists score of 1, 2, 3 * Having approved and signed the informed consent form Exclusion Criteria: * Patients who underwent lobectomy with a diagnosis other than lung cancer * Patients younger than 18 years * Patients with an American Society of Anesthesiologists score of 4 and above * Patients who did not accept informed consent * Patients who refused to participate in the study
References
Publications (6)
- BACKGROUNDCederholm T, Barazzoni R, Austin P, Ballmer P, Biolo G, Bischoff SC, Compher C, Correia I, Higashiguchi T, Holst M, Jensen GL, Malone A, Muscaritoli M, Nyulasi I, Pirlich M, Rothenberg E, Schindler K, Schneider SM, de van der Schueren MA, Sieber C, Valentini L, Yu JC, Van Gossum A, Singer P. ESPEN guidelines on definitions and terminology of clinical nutrition. Clin Nutr. 2017 Feb;36(1):49-64. doi: 10.1016/j.clnu.2016.09.004. Epub 2016 Sep 14. PMID 27642056
- BACKGROUNDMcKenna NP, Bews KA, Al-Refaie WB, Colibaseanu DT, Pemberton JH, Cima RR, Habermann EB. Assessing Malnutrition Before Major Oncologic Surgery: One Size Does Not Fit All. J Am Coll Surg. 2020 Apr;230(4):451-460. doi: 10.1016/j.jamcollsurg.2019.12.034. Epub 2020 Feb 26. PMID 32113029
- BACKGROUNDDetsky AS, McLaughlin JR, Baker JP, Johnston N, Whittaker S, Mendelson RA, Jeejeebhoy KN. What is subjective global assessment of nutritional status? JPEN J Parenter Enteral Nutr. 1987 Jan-Feb;11(1):8-13. doi: 10.1177/014860718701100108. PMID 3820522
- BACKGROUNDKondrup J, Rasmussen HH, Hamberg O, Stanga Z; Ad Hoc ESPEN Working Group. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. Clin Nutr. 2003 Jun;22(3):321-36. doi: 10.1016/s0261-5614(02)00214-5. PMID 12765673
- BACKGROUNDVellas B, Guigoz Y, Garry PJ, Nourhashemi F, Bennahum D, Lauque S, Albarede JL. The Mini Nutritional Assessment (MNA) and its use in grading the nutritional state of elderly patients. Nutrition. 1999 Feb;15(2):116-22. doi: 10.1016/s0899-9007(98)00171-3. PMID 9990575
- BACKGROUNDNeelemaat F, Kruizenga HM, de Vet HC, Seidell JC, Butterman M, van Bokhorst-de van der Schueren MA. Screening malnutrition in hospital outpatients. Can the SNAQ malnutrition screening tool also be applied to this population? Clin Nutr. 2008 Jun;27(3):439-46. doi: 10.1016/j.clnu.2008.02.002. Epub 2008 Apr 18. PMID 18395946