Clinical trial · Observational
Clinical Study of Glycosylated Extracellular Vesicles for Early Diagnosis of Breast Cancer
miRNAs of Circulating Glycosylated Extracellular Vesicles as Biomarkers for Early Diagnosis of Breast Cancer Patients
NCT05417048CI-TRIAL-00064198unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective, single-center, non-randomized, cohort study designed to evaluate the clinical diagnostic performance of glycosylated extracellular vesicles and their contents for early detection of breast cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood Sample | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Breat cancer
- description
- Histologically confirmed breast cancer patients(Stage I-III)
- interventionNames
- Diagnostic Test: Blood Sample
- label
- Benign breast disease
- description
- Histologically confirmed breast fibroma, intraductal papilloma,mammary hyperplasia, breast cyst etc
- interventionNames
- Diagnostic Test: Blood Sample
- label
- Healthy control
- description
- No breast lesions detected by clinical examination/mammography/ultrasound/breast magnetic resonance imaging (MRI)
- interventionNames
- Diagnostic Test: Blood Sample
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients≥18 years old； 2. Histologically confirmed breast cancer patients，Benign breast disease （ig. breast fibroma, intraductal papilloma,mammary hyperplasia, breast cyst）or No breast lesions detected by clinical examination/mammography/ultrasound/breast magnetic resonance imaging (MRI) 3. Previous not received preoperative radiotherapy, chemotherapy, endocrine therapy, immunotherapy, or other anticancer treatments. 4. Subjects signed informed consent； Exclusion Criteria: 1. A history of prior or concomitant malignancies; 2. advanced stage breast cancer (stage IV)； 3. Patients were accompanied by severe organic diseases such as heart and cerebral disease, and liver and kidney disease.； 4. Pregnant or lactating women ； 5. Suspected or confirmed lesion was surgically removed； 6. Patients with incomplete clinical data； 7. Patients with poor compliance； 8. Patients with severe mental illness； 9. Patients had received blood transfusions during one month一；
References
Publications (0)
Data not yet available
No reference posted for this study.