Clinical trial · Interventional
Transoral Endoscopic Thyroidectomy by Vestibular Approach (TOETVA)
Transoral Endoscopic Thyroidectomy by Vestibular Approach (TOETVA) Compared to Conventional Thyroidectomy by Cervical Approach: a Randomized Clinical Trial
NCT05412680CI-TRIAL-00077124TOETVAunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Prospective study carried out with ICESP (instituto do Câncer do Estado de São Paulo) patients with thyroid disease with surgical indication
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Cancer | Malignant Thyroid Gland Neoplasm | CURATED_EXACT | 0.92 |
| Thyroid Diseases | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| conventional thyroidectomy | Procedure | — | UNRESOLVED |
| TOETVA | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- TOETVA
- description
- Patients submitted to transoral endoscopic thyroidectomy by vestibular approach
- interventionNames
- Procedure: TOETVA
- type
- ACTIVE_COMPARATOR
- label
- CONVENTIONAL THYROIDECTOMY
- description
- Patients submitted to conventional open thyroidectomy by cervical approach
- interventionNames
- Procedure: conventional thyroidectomy
Primary outcomes (8)
- measure
- To compare TOETVA technique with conventional thyroidectomy in terms of operative time
- timeFrame
- 1 year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * history of hypertrophic scarring and/or motivation to avoid cervical scarring, * maximum diameter of the thyroid \< 10 cm and of the dominant nodule \< 6 cm, * estimated thyroid volume \< 45 ml * benign lesion (multinodular goiter, cyst), * indeterminate nodule (Bethesda III or IV), * suspicious nodule for well-differentiated thyroid carcinoma (Bethesda V and VI) \< 2 cm Exclusion Criteria: * history of previous surgery or irradiation in the head and neck region and superior mediastinum * evidence of clinical hyperthyroidism * preoperative recurrent nerve palsy * lymph node metastasis * extra-thyroid extension * plunging goiter * oral abscess
References
Publications (0)
Data not yet available
No reference posted for this study.