Clinical trial · Observational
St. Paul's Advanced Resection Center Cohort for Colorectal Neoplasia (SPARC-C)
The St. Paul's Hospital Advanced Endoscopic Resection Centre Cohort for Colorectal Neoplasia (SPARC-C): A Prospective Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The SPARC-C study is a prospective, multi-institutional observational study of patients referred for the management of large (≥ 20mm) non-pedunculated colorectal polyps (LNPCPs). Patients are managed consistent with current standards of care. Prospectively collected data includes: patient clinicodemographic details, lesion details, procedural details, and clinical outcomes.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Adenoma | Colon Adenoma | ONTOLOGY_EXACT | 0.98 |
| Colon Lesion | — | UNRESOLVED | — |
| Colon Polyp | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic tissue resection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Large non-pedunculated colorectal polyp (LNPCP)
- description
- Patients referred to St. Paul's Hospital for endoscopic management of a large (≥20mm) non-pedunculated colorectal polyp (LNPCP).
- interventionNames
- Procedure: Endoscopic tissue resection
Primary outcomes (2)
- measure
- Technical Success of Endoscopic Procedure
- timeFrame
- Intra-procedure
- description
- Complete removal of all visible polypoid tissue during index procedure.
- measure
- Clinical Success of Endoscopic Procedure
- timeFrame
- 6 months
- description
- Technical success and the avoidance of surgery for large non-pedunculated colorectal polyps (LNPCPs) referred for endoscopic resection, assessed at first surveillance colonoscopy. LNPCPs with features consistent with invasive disease and directly referred for surgery are excluded.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients ≥ 18 years of age referred for the management of an LNPCP * Able to provide informed consent. Exclusion Criteria: * Unable to provide informed consent * Pregnant or lactating women.
References
Publications (0)
Data not yet available