Clinical trial · Observational
Minimally Invasive Versus Open Surgery for PHC
Minimally Invasive Versus Open Surgery for Perihilar Cholangiocarcinoma(PHC)：A Multicenter Real-world Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Brief Summary: This is a multicentric, retrospective, real-world study to investigate the surgical outcomes of minimally invasive surgery compared with open surgery for Perihilar Cholangiocarcinoma (PHC), with the perioperative characteristics and long-term overall survival being compared. We aimed to find out whether the minimally invasive surgery is safe or feasible for PHC. And we also want to find out patients with what kind of characteristic can be benefit from the minimally invasive surgery compared with the open approach.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Perihilar Cholangiocarcinoma | Hilar Cholangiocarcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- minimally invasive surgery
- interventionNames
- Other: No intervention
- label
- open surgery
- interventionNames
- Other: No intervention
Primary outcomes (2)
- measure
- Postoperative length of stay
- timeFrame
- up to 90 days
- description
- defined as the time from being admitted to hospital to discharge
- measure
- Overall survival
- timeFrame
- through study completion, an average of 5 year
- description
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: Histologically confirmed PHC. Exclusion Criteria: 1. Peritoneal seeding or metastasis to the liver, para-aortic lymph nodes, or distant sites; 2. Non-adenocarcinoma histology; 3. Incomplete clinical data.
References
Publications (1)
- DERIVEDWang M, Qin T, Zhang H, Li J, Deng X, Zhang Y, Zhao W, Fan Y, Li D, Chen X, Feng Y, Zhu S, Xing Z, Yu G, Xu J, Xie J, Dou C, Ma H, Liu G, Shao Y, Chen W, Liu J, Liu J, Yin X, Qin R. Laparoscopic versus open surgery for perihilar cholangiocarcinoma: a multicenter propensity score analysis of short- term outcomes. BMC Cancer. 2023 May 3;23(1):394. doi: 10.1186/s12885-023-10783-9. PMID 37138243