Clinical trial · Observational
CAR-T Cell Therapy in Patients With Hematological Malignancies
Retrospective Analysis of the Use of CAR-T Cell Therapy in Patients With Hematological Malignancies in Spain
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The prognosis of relapsed or refractory lymphoblastic leukaemia (ALL) and diffuse large B-cell lymphoma (DLBCL) is poor with conventional treatment with complete response rates around 25-30% with a median progression-free survival (PFS) of around 2 months and 7 months, respectively, despite the use of allogeneic and autologous haematopoietic stem cell transplantation. The recent introduction of CAR-T (Chimeric Antigen Receptor T-cells) therapy as a therapeutic option has been a breakthrough in the management of these entities.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| CART Therapy | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Progression free survival
- timeFrame
- 6 month
- description
- Patients who relapse or progress at 6 month after CART infussion.
- measure
- Progression free survival
- timeFrame
- 12 month
- description
- Patients who relapse or progress at 12 month after CART infussion.
- measure
- Progression free survival
- timeFrame
- 24 month
- description
- Patients who relapse or progress at 24 month after CART infussion.
Secondary outcomes (3)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Adult patients \>18 y/o * Patients receiving CAR-T cell therapy in Spain, since 2018. Exclusion Criteria: T * Patients receiving CART therapy as part of a clinical trial.
References
Publications (0)
Data not yet available