Clinical trial · Interventional
Meaning-Centered Pain Coping Skills Training for Cancer Pain
Meaning-Centered Pain Coping Skills Training: A Randomized Controlled Trial of a Psychosocial Intervention for Advanced Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is a randomized controlled trial of a psychosocial pain management intervention called, Meaning-Centered Pain Coping Skills Training (MCPC). Patients with advanced solid tumor cancer and pain interference will be randomized to MCPC or a standard care control condition. Patient-reported outcomes will be assessed at baseline and 8- and 12-week follow-ups. The risk and safety issues in this trial are low and limited to those common to a psychosocial intervention (e.g., loss of confidentiality).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Advanced Solid Tumor | Solid Neoplasm | CURATED_BROADER | 0.80 |
| Pain | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Meaning-Centered Pain Coping Skills Training | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Meaning-Centered Pain Coping Skills Training
- description
- Four, 45-60 minute, videoconference-delivered sessions focus on training participants in cognitive and behavioral skills (e.g., guided imagery, activity pacing) for managing pain.
- interventionNames
- Behavioral: Meaning-Centered Pain Coping Skills Training
- type
- NO_INTERVENTION
- label
- Standard Care
- description
- Information and referrals for free services available through the Duke Cancer Patient Support Program.
Primary outcomes (1)
- measure
- Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Interference-Short Form
- timeFrame
- 8-week follow-up
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Stage IV solid tumor cancer diagnosis * Eastern Cooperative Oncology Group (ECOG) performance status of 2 or lower * At least one clinical pain severity rating \> 0 out of 10 in past month * At least moderate pain interference (8-item Patient-Reported Outcomes Measurement Information System \[PROMIS\] Pain Interference T-score \>/= 55) in the past week at telephone screening * Ability to speak and read in English * Age \>/= 18 years. Exclusion Criteria: * Significant cognitive impairment as indicated in medical chart or during telephone screening * Serious untreated mental illness * Primary brain cancer diagnosis * Previous engagement in Pain Coping Skills Training or Meaning-Centered Psychotherapy * Enrollment in hospice at screening
References
Publications (0)
Data not yet available