Clinical trial · Interventional
Adapted Physical Activity for Children Treated With Cancer and Insulin Sensitivity
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main objective of this study is to evaluate the evolution of the sensitivity to insulin, a hormone that acts on sugar in the body, as well as other metabolic, motor and nutritional elements of children with cancer, according to the practice of intense physical activities or stretching. In view of the scientific work on this subject, it is expect to observe that the practice of intense physical activities will improve the results of the children in the metabolic, motor and nutritional evaluations, compared to the stretching program.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pediatric Cancer | Childhood Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Adapted Physical Activity Strong | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Adapted physical activity Strong
- interventionNames
- Other: Adapted Physical Activity Strong
- type
- ACTIVE_COMPARATOR
- label
- Adapted physical activity Soft
- interventionNames
- Other: Adapted Physical Activity Strong
Primary outcomes (1)
- measure
- Insulin Sensitivity
- timeFrame
- 6 months
- description
- Homeostasis Model Assessment of Insulin Resistance
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 5 Years
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * age between 5 and 18 years old; * have a solid cancer or hematological disease; * be treated for the first time in pediatric oncology and hematology department; * have an estimated life expectancy at diagnosis of more than 6 months. Exclusion Criteria: * present a physical and/or psychological impossibility to follow an adapted physical activity program; * have a pre-existing heart disease that is not suitable for adapted physical activities; * have a known type 1 diabetes * have an obesity defined by a body mass index greater than or equal to the International Obesity Task Force 25 threshold
References
Publications (1)
- DERIVEDThomas J, Filleron T, Auriol F, Laurens C, Pasquet M. Study protocol of an early randomized intervention trial assessing the metabolic effects of two levels of exercise intensity in children undergoing cancer treatment: the APACIS study. BMC Cancer. 2025 May 9;25(1):850. doi: 10.1186/s12885-025-14235-4. PMID 40346598