Clinical trial · Interventional
Camrelizumab Combined With Apatinib Mesylate
A Real World Study of Camrelizumab Combined With Apatinib Mesylate in Solid Tumors
NCT05380986CI-TRIAL-00058592unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to observe the safety of camrelizumab combined with apatinib mesylate in the treatment of solid tumors
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solid Tumor | Solid Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Camrelizumab combined with apatinib mesylate | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Camrelizumab combined with apatinib mesylate
- description
- Camrelizumab 200 mg, IVGTT D1, apatinib mesylate, once daily. The specific prescription is determined by the investigator. Continued use until disease progression, unacceptable toxicity, or withdrawal for other reasons.
- interventionNames
- Drug: Camrelizumab combined with apatinib mesylate
Primary outcomes (1)
- measure
- AE
- timeFrame
- up to 2 years
- description
- any adverse medical event that occurs after a subject or clinical study receives a drug or treatment regimen
Secondary outcomes (3)
- measure
- Objective response rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age: ≥18 years old, male or female; 2. ECOG score is 0\~2; 3. Patients with solid tumors confirmed by pathology or histology; 4. At least one measurable lesion (according to RECIST V 1.1); 5. For patients who have failed first-line or second-line treatment or who cannot tolerate standard treatment regimens for solid tumors. 6. Estimated survival ≥3 months; 7. Patients who have used immunosuppressants or antiangiogenic drugs in the past are not excluded; 8. For women who have not undergone menopause or surgical sterilization, agree to abstain from sex or use an effective contraceptive method during treatment and for at least 7 months after the last dose given in study treatment; 9. Researchers think they can benefit; 10. Voluntarily participate in the study and sign the informed consent; Exclusion Criteria: 1. Pregnant or lactating women; 2. Except patients with contraindications to camrelizumab and/or apatinib mesylate, that is, those allergic to camrelizumab and its excipients; Allergic to apatinib mesylate should be prohibited; It should be contraindication for patients with active bleeding, ulcers, intestinal perforation, intestinal obstruction, hypertension beyond drug control within 30 days after major surgery, class III-IV cardiac insufficiency (NYHA standard), and severe hepatic or renal insufficiency (Class 4). 3. Those deemed unsuitable for inclusion by doctors; 4. The researchers determined there was a high risk that the tumor would invade important blood vessels and cause fatal hemorrhages during the follow-up study
References
Publications (0)
Data not yet available
No reference posted for this study.