Clinical trial · Interventional
Thyroid Nodule Gene Sequencing in a Danish Population
Thyroid Nodule Gene Sequencing in a Danish Population - a Pilot Study
NCT05377736CI-TRIAL-00084367active not recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This pilot study aims at describing the prevalence and distribution of molecular alterations in thyroid nodules of benign and malignant origin at the level of DNA and RNA in a Danish population. Patients with thyroid nodules suspected of malignancy is included prospectively. Tissue samples are collected for molecular analyses form surgical specimens and bloodsamples, and preoperative clincial features are registered.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Cancer | Malignant Thyroid Gland Neoplasm | CURATED_EXACT | 0.92 |
| Thyroid Nodule (Diagnosis) | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Molecular analyses | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Molecular testing
- description
- Descriptive and explorative study including identical molecular analyses applied to all included patients
- interventionNames
- Genetic: Molecular analyses
Primary outcomes (4)
- measure
- DNA alterations
- timeFrame
- Two years
- description
- Whole genome sequencing by next generation sequencing
- measure
- RNA alterations
- timeFrame
- Two years
- description
- Total RNA sequencing including circular RNA, micro RNA and messenger RNA
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Thyroid nodule \>1.5 cm * BSRTC: IV, V, og VI Exclusion Criteria: * No surgical specimen available * Purely cystic nodules
References
Publications (0)
Data not yet available
No reference posted for this study.