Clinical trial · Interventional
Effect of Fresh Gas Flow on Emergence Time
Effect of Fresh Gas Flow on Emergence Time in the Patients Undergoing Transurethral Resection of Bladder Tumor: A Randomized Controlled Clinical Trial
NCT05376631CI-TRIAL-00060421completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the effect of fresh gas flow on emergence time in patients undergoing transurethral resection of bladder tumor.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer | Malignant Bladder Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Fresh gas flow of 10 L/min | Procedure | — | UNRESOLVED |
| Fresh gas flow of 5 L/min | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Group Five
- description
- For emergence from general anesthesia, a fresh gas flow of 5 L/min is used.
- interventionNames
- Procedure: Fresh gas flow of 5 L/min
- type
- EXPERIMENTAL
- label
- Group Ten
- description
- For emergence from general anesthesia, a fresh gas flow of 10 L/min is used.
- interventionNames
- Procedure: Fresh gas flow of 10 L/min
Primary outcomes (1)
- measure
- Emergence time
- timeFrame
- From end of surgery to extubation (assessed up to 30 minutes after surgery)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 79 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who are scheduled transurethral resection of bladder tumor under general anesthesia * Patients aged between 20 and 79 years old * American Society of Anesthesiologists physical status ≤2 * Patients who are voluntarily agreed to this clinical study Exclusion Criteria: * A long operation (2 hours or longer) * Hearing disturbance * Cognitive disorder * Psychiatric substance abuse * Patient's denial
References
Publications (6)
- BACKGROUNDGaya da Costa M, Kalmar AF, Struys MMRF. Inhaled Anesthetics: Environmental Role, Occupational Risk, and Clinical Use. J Clin Med. 2021 Mar 22;10(6):1306. doi: 10.3390/jcm10061306. PMID 33810063
- BACKGROUNDBrioni JD, Varughese S, Ahmed R, Bein B. A clinical review of inhalation anesthesia with sevoflurane: from early research to emerging topics. J Anesth. 2017 Oct;31(5):764-778. doi: 10.1007/s00540-017-2375-6. Epub 2017 Jun 5. PMID 28585095
- BACKGROUNDBaum JA. Low-flow anesthesia: theory, practice, technical preconditions, advantages, and foreign gas accumulation. J Anesth. 1999;13(3):166-74. doi: 10.1007/s005400050050. No abstract available. PMID 14530937
- BACKGROUNDSakata DJ, Gopalakrishnan NA, Orr JA, White JL, Westenskow DR. Hypercapnic hyperventilation shortens emergence time from isoflurane anesthesia. Anesth Analg. 2007 Mar;104(3):587-91. doi: 10.1213/01.ane.0000255074.96657.39. PMID 17312214
- BACKGROUNDDifficult Airway Society Extubation Guidelines Group; Popat M, Mitchell V, Dravid R, Patel A, Swampillai C, Higgs A. Difficult Airway Society Guidelines for the management of tracheal extubation. Anaesthesia. 2012 Mar;67(3):318-40. doi: 10.1111/j.1365-2044.2012.07075.x. PMID 22321104
- DERIVEDPark JY, Yu J, Kim CS, Baek JW, Jo Y, Kim YK. Comparison of the effects of 5 and 10 L/minute fresh gas flow on emergence from sevoflurane anesthesia: A randomized clinical trial. Medicine (Baltimore). 2023 Jul 21;102(29):e34406. doi: 10.1097/MD.0000000000034406. PMID 37478213