Clinical trial · Observational
Evaluation of Cognitive and Motor Neurological Disorders in the Short and Long Term After Surgery for the Removal of a Diffuse Low-grade Glioma of the Supplementary Motor Area
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Background : The supplementary motor area is the most common/preferential brain location of LGG. This area plays an important role in many motor and cognitive functions such as motor initiation, bimanual coordination and executive functions. Many studies describe the supplementary motor area syndrome resulting from lesions in this area. News managements for LGGs consisting in intraoperative mapping in awake patients reduce significantly neurological disorders and increase also the overall survival . However, the literature does not provide data concerning motor and cognitive functions in a long term and their consequences in the quality of life of patients. Objective : The aim of our research project is to identify whether there are some motor or neurocognitive deficit in the short and the long term in a population of patients who have medical story of LGG resection in the supplementary motor area.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cognitive Disorders | — | UNRESOLVED | — |
| Low-grade Glioma | Low Grade Glioma | ONTOLOGY_EXACT | 0.98 |
| Motor Disorders | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Test battery | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Case
- description
- patients with a history of surgical removal of diffuse low grade glioma located in the supplementary motor area
- interventionNames
- Other: Test battery
- label
- Control
- description
- patients with a history of surgical removal of diffuse low-grade glioma located in another brain area
- interventionNames
- Other: Test battery
Primary outcomes (2)
- measure
- motor tests in the case group - 400 point assessment
- timeFrame
- inclusion visit
- description
- analysis of the scores obtained at the tests 4 tests : * Hand mobility * Grip strength * Single-handed grasp and movement of objects * Two-handed grasp and movement of objects Minimum value = 0 Maximum value = 100 100/100 means that the various tests regain good motor skills and hand grasp
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 18 years of age or older * Have a history of low-grade diffuse glioma resection * Visiting the University Hospital for a follow-up neurosurgical consultation * Underwent awake surgery Exclusion Criteria: * Presence of cognitive disorders that do not allow the proposed test battery to be performed * Under guardianship or curatorship * Opposition to the participation to the research
References
Publications (0)
Data not yet available