Clinical trial · Observational
Real-world Resource Use and Costs of CAR-T Therapies in Diffuse Large B-cell Lymphoma (DLBCL)
Real-world Resource Use and Costs of CAR-T Therapies in Diffuse Large B-cell Lymphoma (DLBCL): Inpatient and Outpatient Settings
NCT05366257CI-TRIAL-00059486completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A retrospective, non-interventional cohort study was used to address the study objectives. This study aimed to provide a better understanding of real-world healthcare resource utilization (HRU) and healthcare reimbursement costs associated with CAR-T therapy among patients with r/r Diffuse Large B-cell Lymphoma (DLBCL).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Diffuse Large B-cell Lymphoma (DLBCL) | Diffuse Large B-Cell Lymphoma | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Allo-HSCT cohort | Other | — | UNRESOLVED |
| CAR-T | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- CAR-T: Inpatient (IP) Cohort
- description
- Patients received CAR-T infusion in IP setting
- interventionNames
- Other: CAR-T
- label
- CAR-T: Outpatient (OP) Cohort
- description
- Patients received CAR-T infusion in OP setting
- interventionNames
- Other: CAR-T
- label
- Allo-HSCT cohort
- description
- Patients received allogeneic hematopoietic stem cell transplant
- interventionNames
- Other: Allo-HSCT cohort
Primary outcomes (11)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: CAR-T cohort: * Patients had at least one International Classification of Diseases, Tenth Revision (ICD- 10) diagnosis code for DLBCL. * Patients received CAR-T therapy following DLBCL diagnosis. The administration date of CAR-T therapy was defined as the index date. Patients who received both CAR-T therapy and allo-HSCT were classified based on the first treatment that the patient received * Patients were at least 18 years of age as of the index date * Patients had at least three months of continuous eligibility in the Medicare Part A and Part B data before the index date. Since 2019 Part D data is not available in the current data cut, eligibility requirement in the Part D data was not required Patients were further classified into CAR-T IP and CAR-T OP cohorts depending on where the administration occurred. Allo-HSCT cohort: * Patients had at least one ICD-10 diagnosis code for DLBCL. * Patients received allo-HSCT following DLBCL diagnosis. The date of allo-HSCT procedure was defined as the index date. Patients who received both CAR-T therapy and allo-HSCT were classified based on the first treatment the patient received * Patients were at least 18 years of age as of the index date * Patients had at least three months of continuous eligibility in the Medicare Part A and Part B data before the index date. Since 2019 Part D data is not available in the current data cut, eligibility requirement in the Part D data was not required Exclusion Criteria: \- Patients had a medical claim associated with a clinical trial (ICD-9 CM code V70.7; ICD-10 CM code Z00.6) during one month before and after the index date
References
Publications (0)
Data not yet available
No reference posted for this study.