Study of Microwave Spherical Ablation and Traditional Microwave Ablation in Single Hepatocellular Carcinoma ≤5cm

Inclusion Criteria:

1. Patient has high risk factors for HCC and was first diagnosed of HCC by by contrast-enhanced imaging (CECT/CEMRI/CEUS) and/or pathology ;
2. Age range 18 to 75 years old;
3. Single lesion with tumor diameter ≤5cm;
4. Patient refuses surgery and determines to undergo microwave ablation
5. Liver function Child Pugh A or B;
6. No extrahepatic metastasis or portal invasion;
7. Patient signs the informed consent.

Exclusion Criteria:

1. The lesion has received treatment, including local ablation therapy and TACE therapy, etc;
2. With portal vein invasion or extrahepatic metastases;
3. Patient is with severe cardiopulmonary insufficiency.
4. Patient is a pregnant or breastfeeding women.
5. Patient is considered to be unsuitable to participate in the study