Clinical trial · Interventional
Interventional Study on DEterminants and Factors of Physical ACtivity After Treatments in Oncology
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Benefits of physical activity (PA) as supportive care in cancer have been widely demonstrated by the scientific community. However, survivors who have completed chemo-radio-immunotherapy treatments doesn't achieve PA recommendations on average. This reinforces the need to identify factors influencing PA level, and to propose a multilevel model (macro-, meso-, micro-level) to understand better what facilitates the adoption and maintenance of active behaviour and what hinders it. To date, there is no ecological model in France explaining this behaviour in the post-treatment phase of breast, colorectal, prostate, and lung cancers. From this initial model, we seek to design an educational and motivational intervention in PA. Thus, the investigators propose to test the feasibility of implementing an individualized program to increase and maintain level of physical activity and to decrease sedentary behaviours in physically inactive cancer survivors. This program is based through and identification of barriers and facilitators of an active lifestyle among this population.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Colo-rectal Cancer | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Physical activity program | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Intervention
- description
- Feasibility group. Single group (intervention group) will be given access to the DEFACTO intervention for twelve-weeks.
- interventionNames
- Behavioral: Physical activity program
Primary outcomes (1)
- measure
- Change of physical activity (connected device)
- timeFrame
- One week before initiation of DEFACTO intervention, during the intervention and intervention at Month 3 and Month 6 and Month 12
- description
- Average daily steps, distance traveled, floors climbed, heart rate, cumulative duration of activities of moderate and vigorous intensities using VIVOSMART4® (Garmin)
Secondary outcomes (7)
- measure
- Change of physical activity by the Global Physical Activity Questionnaire (GPAQ)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * 18 years ≤ age \< 75 years * survivors of primary non-metastatic breast, lung, prostate or colorectal cancer (stage I, II or III and primary, second and relapse included) * 3 weeks to 20 years post-treatment (surgery, chemotherapy, radiation therapy and/or immunotherapy) not including hormonal therapy * Whose ability to participate in the APA intervention has been certified by a medical certificate issued by physician * Availability and willingness to invest in the DEFACTO study during the program (3 months) and during the post-program follow-up (12 months) * Participating, on average, in no more than 150 minutes of moderate physical activity or no more than 75 minutes of vigorous activity per week * Average at least 6 hours a day of sedentary behaviours * Able to read, understand and complete questionnaires in French * Able to use connected device (Vivosmart4®) and to perform simple operating actions (press a button, recharge the battery) * possessing a smartphone which can download Garmin Connect application ® * Able to walk unassisted * French speaking and living in France * having signed the consent form Exclusion Criteria: * Current evidence of metastatic disease * Having an absolute contraindication by a physician to practice PA * Using treatments that influence blood pressure, cardiotoxic drugs, painkillers (morphinics); * Using cane or walking aid * Deprived of liberty by judicial or administrative decision * Person under guardianship or curatorship * Pregnancy and/or lactating women * Being diagnosed of any cardiac abnormalities
References
Publications (1)
- DERIVEDAumaitre A, Gagnayre R, Foucaut AM. Determinants and Factors of Physical Activity After Oncology Treatments (DEFACTO) in Metropolitan France: Protocol of a Mixed Methods Study and Intervention. JMIR Res Protoc. 2024 May 16;13:e52274. doi: 10.2196/52274. PMID 38753415