Clinical trial · Observational
Cardiopulmonary Exercise Test Data Averaging Methods and Preoperative Risk Assessment
Influence of Different Data Averaging Methods on Preoperative Risk Assessment Using Cardiopulmonary Exercise Testing in Patients Scheduled for Colorectal Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cardiopulmonary exercise testing (CPET) is used for preoperative risk assessment in patients with colorectal cancer who need to undergo surgery. For presentation and interpretation purposes, CPET data are averaged by using a time- or breath-based average. It is uncertain to what extent differences in data averaging methods influence the numerical value of preoperative CPET-derived variables used for risk assessment. Therefore, the primary aim of this study is to investigate the influence of different CPET data averaging intervals on the numerical values of CPET-derived variables used for preoperative risk assessment in patients scheduled for elective colorectal cancer surgery. The secondary aim is to elucidate the impact of data-averaging intervals on classification of patients into a low- or high-risk category for postoperative complications based on known risk assessment thresholds.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Colorectal Neoplasms Malignant | — | UNRESOLVED | — |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CPET/Cardiopulmonary Exercise Test | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patiënts who underwent a CPET prior to elective colorectal surgery investigate fitness level.
- description
- Patients considered for colorectal cancer surgery who were ≥18 years of age, had a score ≤7 metabolic equivalents of task on the veterans-specific activity questionnaire.
- interventionNames
- Diagnostic Test: CPET/Cardiopulmonary Exercise Test
Primary outcomes (6)
- measure
- Influence of different CPET data averaging intervals on the numerical values of CPET-derived variables.
- timeFrame
- Baseline, pre surgery
- description
- To assess the influence of different CPET data averaging intervals on the numerical the numerical values of VO2VAT,
- measure
- Influence of different CPET data averaging intervals on the numerical values of CPET-
- timeFrame
- Baseline, pre surgery
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patiënts with colorectal cancer, considered for surgery. * A score of ≤7 metabolic equivalents of task on the veterans-specific activity questionnaire and therefore performed preoperative CPET as a part of a prehabilitation study Exclusion Criteria: * Patiënt unable to perform CPET.
References
Publications (1)
- DERIVEDFranssen RFW, Sanders BHE, Takken T, Vogelaar FJ, Janssen-Heijnen MLG, Bongers BC. Influence of different data-averaging methods on mean values of selected variables derived from preoperative cardiopulmonary exercise testing in patients scheduled for colorectal surgery. PLoS One. 2023 Mar 16;18(3):e0283129. doi: 10.1371/journal.pone.0283129. eCollection 2023. PMID 36928094