Clinical trial · Interventional
Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery Download
Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This will be a prospective, (NSR), single-center feasibility study of the Olympus VE2 NIR Imaging System to assess perfusion using NIR during minimally invasive esophagectomy and pulmonary segmentectomy. The aims of the study are: 1\. To utilize NIR intraoperative imaging with the Olympus VE2 NIR Imaging System to: i. Characterize gastric conduit perfusion during esophagectomy and, ii. Identify segmental anatomy during sublobar pulmonary resection (segmentectomy) after intraoperative, intravenous delivery of low-dose 0.15 mg/kg of ICG.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Lesion | — | UNRESOLVED | — |
| Lung Neoplasms | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Indocyanine green | Drug | — | UNRESOLVED |
| Olympus VE2 NIR Imaging System | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- During Minimally Invasive Pulmonary Segmentectomy (Group 2)
- interventionNames
- Device: Olympus VE2 NIR Imaging System
- Drug: Indocyanine green
- type
- EXPERIMENTAL
- label
- During Minimally Invasive Esophagectomy (Group 1)
- interventionNames
- Device: Olympus VE2 NIR Imaging System
- Drug: Indocyanine green
Primary outcomes (2)
- measure
- To utilize NIR intraoperative imaging with the Olympus VE2 NIR Imaging System for esophagectomy patients.
- timeFrame
- During surgery
- description
- Fluorescent intensity, visualization of the intersegmental plane with NIR imaging, image quality will all be ranked by the surgeon as "below standard, average, or good" compared to the standard of care as they identify segmental anatomy during sublobar pulmonary resection (segmentectomy) after intraoperative, intravenous delivery of low-dose 0.15 mg/kg of ICG.
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: -Subject has a suspicious lung lesion for which a minimally invasive segmentectomy is planned -OR- sub-ject has an esophageal lesion for which an esophagectomy is planned - * Subject is 18 years of age or older * Subject is willing and able to provide informed consent Exclusion Criteria: * Subject is not eligible for surgical resection as determined by the treating physician * Subject has known or suspected allergy to Iodine, shellfish or intravenous contrast * Subject is not eligible or considered high risk for surgical resection as determined by pre-operative spirometry * Subject is female and of childbearing age who is currently pregnant or who is planning to become pregnant within the study * Subject is unable and unwilling to provide informed consent * Subject has liver disease or is taking drugs impact liver metabolism.
References
Publications (2)
- BACKGROUNDDeLong JC, Kelly KJ, Jacobsen GR, Sandler BJ, Horgan S, Bouvet M. The benefits and limitations of robotic assisted transhiatal esophagectomy for esophageal cancer. J Vis Surg. 2016 Sep 8;2:156. doi: 10.21037/jovs.2016.09.01. eCollection 2016. PMID 29078542
- BACKGROUNDSiegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin. 2019 Jan;69(1):7-34. doi: 10.3322/caac.21551. Epub 2019 Jan 8. PMID 30620402