Clinical trial · Interventional
Braining- Aerobic Physical Activity as Add on Treatment in Bipolar Depression
Braining - A Randomized Controlled Study on Moderate-vigorous Aerobic Physical Exercise (PE) as an add-on Treatment in Bipolar Disorder. Effects on Recovery Time and Long-term Prevention From Bipolar Depression
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Difficulties recruiting
Summary
Brief summary (as posted)
Hypothesis: the hypothesis of the study is that aerobic physical exercise (PE) performed with the method Braining accelerates recovery from bipolar depression as well as improves psychiatric and somatic health in individuals with bipolar depression Method: a randomized controlled trial with 54 patients with bipolar depression are randomized to 6 weeks of either 1) supervised aerobic PE 3 times/week, 2) supervised relaxation/stretching 3 times/week or 3) information about PE but no supervised activity.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bipolar Affective Disorder, Currently Depressed, Moderate | — | UNRESOLVED | — |
| Bipolar Affective Disorder; Remission in | — | UNRESOLVED | — |
| Bipolar Depression | — | UNRESOLVED | — |
| Bipolar Disorder | — | UNRESOLVED | — |
| Bipolar I Disorder | — | UNRESOLVED | — |
| Bipolar II Disorder | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Aerobic Physical Exercise | Behavioral | — | UNRESOLVED |
| Information about physical exercise | Behavioral | — | UNRESOLVED |
| Relaxing Physical Exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Braining high intensity
- description
- Moderate to vigorous physical exercise, supervised by psychiatric staff 3 times per week
- interventionNames
- Behavioral: Aerobic Physical Exercise
- type
- ACTIVE_COMPARATOR
- label
- Braining relaxing exercise
- description
- Relaxation, light yoga or stretching exercise, supervised by psychiatric staff 3 times per week
- interventionNames
- Behavioral: Relaxing Physical Exercise
- type
- ACTIVE_COMPARATOR
- label
- Information about physical exercise
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients at Psychiatry Southwest, Karolinska University Hospital Region Stockholm Sweden. * Bipolar disorder * Ongoing depression, defined as a PHQ-9 score of 9 or higher at any occasion 2 weeks before inclusion. Exclusion Criteria: * Severe psychiatric disorder such as mania and psychosis * Medical conditions such as heart- and lung diseases where PE is contraindicated. * Unable to understand written and spoken Swedish language.
References
Publications (0)
Data not yet available