Clinical trial · Interventional
Long Term Bowel Function Following Rectal Cancer Surgery
Long Term Bowel Functional Outcomes Following Anal Sphincter Preserving Surgery for Rectal Cancer: A Single Center Longitudinal Study.
NCT05339763CI-TRIAL-00057953completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
* In this longitudinal study, 171 patients were evaluated and compared based on the radiation therapy they received. * Bowel function was assessed longitudinally with Memorial Sloan Kettering Cancer Center and Wexner scores every 6 months after restoration of bowel continuity. Patients with at least two follow-up visits were included.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bowel; Functional Syndrome | — | UNRESOLVED | — |
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| chemoradiotherapy | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- radiation group
- description
- Those are patient with rectal cancer who underwent preoperative neoadjuvant chemo radiotherapy before surgery.
- interventionNames
- Radiation: chemoradiotherapy
- type
- ACTIVE_COMPARATOR
- label
- non radiation group
- description
- Those are patient with rectal cancer who did not receive preoperative neoadjuvant chemo radiotherapy before surgery.
- interventionNames
- Radiation: chemoradiotherapy
Primary outcomes (1)
- measure
- bowel function
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients of both sexes, * Aged between 18 and 75 years, * Patients with mid and upper rectal cancer (6-15) cm from the anal verge(AV) with or without preoperative chemo radiotherapy. * Patients who underwent low anterior resection(LAR). * Patients who were followed up with at least two outpatient visits for bowel function assessment. Exclusion Criteria: * Patients with recurrent rectal tumors, * Surgically unfit patients, * Patients with tumors infiltrating the puborectalis muscle or external sphincter. * Patients with preoperative fecal incontinence. * Patients who were followed up only once in the outpatient clinic. * Patients with lower rectal cancer less than 6cm from AV, * Patients who underwent abdominoperineal resection(APR) or intersphincteric resection(ISR).
References
Publications (0)
Data not yet available
No reference posted for this study.