Clinical trial · Interventional
Urinary Continence of Female POPRC and OIN
Urinary Continence of Female Pelvic Organ-preserving Radical Cystectomy and Orthotopic Ileal Neobladder: A Randomized Controlled Study
NCT05325216CI-TRIAL-00057765not yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To compare the urinary continence rate and long-term oncological outcomes of pelvic-organ preserving radical cystectomy (POPRC) with orthotopic ileal neobladder (OIN) versus standard radical cystectomy(SRC) with OIN.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Sexual Dysfunction, Physiological | — | UNRESOLVED | — |
| Treatment Outcome | — | UNRESOLVED | — |
| Urinary Bladder Neoplasms | Bladder Neoplasm | ALIAS | 0.90 |
| Urinary Incontinence | — | UNRESOLVED | — |
| Woman | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| POPRC+OIN | Procedure | — | UNRESOLVED |
| SRC+OIN | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- POPRC group
- description
- pelvic-organ preserving radical cystectomy with orthotopic ileal neobladder
- interventionNames
- Procedure: POPRC+OIN
- type
- ACTIVE_COMPARATOR
- label
- SRC group
- description
- standard radical cystectomy with orthotopic ileal neobladder
- interventionNames
- Procedure: SRC+OIN
Primary outcomes (1)
- measure
- day-time and night-time continence rate
- timeFrame
- 6 months
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 55 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. Female patients aged between 55-75. 2. Patients those who are diagnosed with organ-confined urothelial carcinoma（\<pT3） 3. Patients those who are capable for radical cystectomy with orthotopic ileal neobladder. 4. ECOG score between 0-2; 5. Normal renal function; 6. Patients those who volunteer to participate in this study and sign the informed consents. 7. Patients those who are able to cooperate in the study. Exclusion Criteria: 1. Absence of tumour in bladder neck or urethra; 2. Patients thsoe who are diagnosed distant metastasis before surgery. 3. Previous history of malignancy of pelvic organs or surgical resection of pelvic organs; 4. Patients those who are diagnosed with other malignancies.; 5. Patients those who had received pelvic radiotherapy or major pelvic operation. 6. Pregnancy status; 7. Any other conditions that the researcher considers to be excluded from this study
References
Publications (0)
Data not yet available
No reference posted for this study.