Clinical trial · Interventional
New Imaging Procedures and Therapeutic Approach in Basal Cell Carcinoma Management
New Imaging Procedures and Therapeutic Approach in Basal Cell Carcinoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to show that the Nd:YAG laser could be a promising alternative treatment option in the management of low-risk basal cell carcinomas with similar high efficacy rates to surgery, and low recurrence rates evaluated over a time period of one year. Reflectance confocal microscopy, optical coherence tomography and clinical examination are used prior to confirm the clinical diagnosis of the basal cell carcinoma and for premargination of the tumor. The optical coherence tomography will also be used post treatment to confirm clearance of the basal cell carcinoma and to monitor treatment response.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Basal Cell Carcinoma | Basal Cell Carcinoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cynosure Cynergy Nd:YAG Laser 1064nm | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Nd:YAG treatment arm
- interventionNames
- Device: Cynosure Cynergy Nd:YAG Laser 1064nm
Primary outcomes (2)
- measure
- Treatment efficacy of Nd:YAG Laser 1064-nm for low risk basal cell carcinomas
- timeFrame
- 8 weeks after the treatment
- description
- Clearance rate of basal cell carcinomas after 1-3 Nd:YAG laser treatments evaluated by clinical inspectation, dermatosopy and optical coherence tomography.
- measure
- Recurrence Rate after Nd:YAG Laser treatment
- timeFrame
- 12 months
- description
- To assess the recurrence rate after a long-term follow-up of 6 and 12 months
Secondary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: Patients with one or more basal cell carcinoma(s) on head, trunk or extremities * Diagnosed clinically, with a dermatoscope and through noninvasive imaging methods such as reflectance confocal microscopy and optical coherence tomography * H zone \<6mm, M zone \<10mm, L zone \<20mm * Tumor thickness \<2mm * Clearly visible margins Exclusion Criteria: * Pregnancy * \<18 years of age * Current or history of immunosuppression * Prior-treatment of the basal cell carcinoma/ recurrent basal cell carcinomas * History of radiation in the area of basal cell carcinoma appearance
References
Publications (0)
Data not yet available