Clinical trial · Observational
Lymphangioleiomyomatosis, a Study on Cathepsin K
Study of New Potential Biomarkers of Lymphangioleiomyomatosis: Determination of Cathepsin K, Cystatin C, Collagen Telopeptides and Chondroitin Sulfates
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a physiopathological case-control, non-interventional, monocentric study of adult patients with lymphangioleiomyomatosis. The controls are patients followed in neurology at the CHU of Tours for a tuberous sclerosis complex without lymphangioleiomyomatosis, the healthy volunteers are women with neither pulmonary nor renal pathology and recruited at the clinical investigation centre of the CHU of Tours.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymphangioleiomyomatosis | Lymphangioleiomyomatosis | ONTOLOGY_EXACT | 0.98 |
| Tuberous Sclerosis Complex | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 24h urine | Other | — | UNRESOLVED |
| urine sample | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Patientes with lymphangioleiomyomatosis
- description
- no intervention administered. Recruitment in pneumology department
- interventionNames
- Other: 24h urine
- Other: urine sample
- label
- Patientes with tuberous sclerosis complex without Lymphangioleiomyomatosis
- description
- no intervention administered. Recruitment in neurology department
- interventionNames
- Other: 24h urine
- Other: urine sample
- label
- Healthy women volunteers
- description
- no intervention administered. Recruitment in clinical investigation centre
- interventionNames
- Other: 24h urine
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion criteria for patients with lymphangioleiomyomatosis * Age ≥ 18 years * Female carrier of lymphangioleiomyomatosis according to ERS criteria Inclusion criteria for healthy female volunteers * Age ≥ 18 years * Women with no history of lymphangioleiomyomatosis, pulmonary, renal or osteoporotic disease Inclusion criteria for tuberous sclerosis complex patients without lymphangioleiomyomatosis * Age ≥ 18 years * Woman followed for tuberous sclerosis complex for whom a chest CT scan less than 3 years old does not objectify a pulmonary cyst. (= without lymphangioleiomyomatosis) Non-inclusion criteria * Woman under judicial protection * Woman with a urinary tract infection within 15 days * Person who objected to the data processing
References
Publications (0)
Data not yet available