Clinical trial · Interventional
Specificities of the Eccentric Exercise: Energy Expenditure and Nature of Oxidized Substrates
NCT05319704CI-TRIAL-00057679Speed-EnsounknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Main objective of this clinical trial is to compare the oxidation rates of main carbohydrate and lipid substrates during exercises carried out in eccentric dynamic pedaling mode on a cycloergometer compared to concentric exercises (classic pedaling) at the same oxygen consumption (VO2). The hypothesis is that lipid oxidation during an eccentric exercise is higher than lipid oxidation during a concentric exercise, done in humans at the capacity of 30% of VO2max.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Healthy | — | UNRESOLVED | — |
| Men | Multiple Endocrine Neoplasia | ALIAS | 0.90 |
| Overweight | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Kinetics on concentric or excentric mode during test of effort | Other | — | UNRESOLVED |
| Test of effort on cycle on concentric or excentric mode | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- ACTIVE_COMPARATOR
- label
- Test of effort, sub-maximal, progressive, carried out in eccentric mode
- description
- The exercise will start at 10% of VO2max. However, every six minutes, the level of VO2max will be increased by 10%, up to 50%.
- interventionNames
- Other: Test of effort on cycle on concentric or excentric mode
- Other: Kinetics on concentric or excentric mode during test of effort
- type
- PLACEBO_COMPARATOR
- label
- Test of effort, sub-maximal, progressive, carried out in concentric mode
- description
- The exercise will start at 10% of VO2max. However, every six minutes, the level of VO2max will be increased by 10%, up to 50%.
- interventionNames
- Other: Test of effort on cycle on concentric or excentric mode
- Other: Kinetics on concentric or excentric mode during test of effort
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 20 Years
- Maximum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * Male volunteers between 20 and 40 years old (20 ≥ years ≤ 40) * Subjects considered healthy by investigator based on the examination, medical and clinical examination * Body Mass Index between 27 and 35 kg/m² (27 \< BMI \< 35) * Biological check up considered compatible with study participation * Physical check up considered compatible with study participation (no bones, articular or muscular problems) * Person who don't smoke and has no treatment * Person who is in the position to sign informed consent Exclusion Criteria: * Smoking * Person who take any kind of treatments except Paracétamol * All conditions who have interaction with this clinical trial, or who can deteriorate the exercise capacity or the realization of canopy (claustrophobia) * Criteria * Administrative and legal factors * Person who isn't consent * Subject not affiliated with social security * Subject during the exclusion period of a previous study (after verification in the Biomedical Research Volunteers File).
References
Publications (0)
Data not yet available
No reference posted for this study.