Clinical trial · Observational
Lymphoedema Among Persons With Head- and Neck Cancer
Lymphoedema for Persons With Head- and Neck Cancer
NCT05316974CI-TRIAL-00096394completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Lymphedema in the head and neck area is common after treatment for head and neck cancer. The aim of the research project is: • to assess the prevalence of lymphedema in patients with head and neck cancer (HNC) by measuring the amount of tissue water in the head and neck area before and after different kinds of cancer treatment, and to evaluate the quality of life before and after cancer treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer of Head and Neck | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Prevalence of lymphoedema | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Change in level of tissue water
- timeFrame
- Baseline and after 3 and 9 months
- description
- Change in tissue water in the head and neck before and after cancer treatment
Secondary outcomes (4)
- measure
- QoL
- timeFrame
- 3 and 9 months
- description
- Quality of life measured by LyQLI
- measure
- Change in QoL QLQ-c30
- timeFrame
- Baseline and after 3 and 9 months
- description
- Change in Quality of life measured by QLQ-c30
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Biopsy or cytology confirmed HNC (all malignant types are accepted) from the oropharynx (OPC), oral cavity (OC) or neck metastases from unknown primary cancer of the head and neck (CUP). * Tumour stage T1-4, N0-3. * Planned for treatment with curative intent as recommended at the multidisciplinary tumour board. * Age \>18 years. Able to give informed consent Exclusion Criteria: * Previous treatment of HNC or radiation to the head and neck area. * Planned surgery that includes free tissue transfer or pedicled flaps in the neck (local facial pedicled flaps are accepted). * Planned neck dissection involving less than three regions of the neck. * Planned proton therapy. * Pre-treatment surgery or Botox injections in the tissue in the head and neck area. * Pregnancy
References
Publications (0)
Data not yet available
No reference posted for this study.